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Calycosin CAS No. 20575-57-9

Short Description:

Calycosin;7,3’-dihydroxy-4’-methoxyisoflavone

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Product Detail

Product Tags

Essential Information

【Common name】pistil isoflavone

【English Name】calycosin

【CAS No.】 20575-57-9

【Molecular Weight】284.263

【Density】 1.4 ± 0.1 g / cm3

【Boiling Point】 536.8 ± 50.0 ° C at 760 mmHg

【Molecular Formula】 C16H12O5

【Melting Point】 n / A

Application of Calycosin

Calycosin is a natural compound with antioxidant and anti-inflammatory activities.

Bioactivity of Calycosin

Description: Calycosin is a natural compound with antioxidant and anti-inflammatory activities.

Related categories:

Signal path > > other > > other

Research field > > cancer

Natural Products > > flavonoids

Reference:

[1]. Zhou Y, et al. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 family proteins. Tumour Biol. 2015 Feb 12.

[2]. Chen J, et al. Calycosin and genistein induce apoptosis by inactivation of HOTAIR/p-Akt signaling pathway in human breast cancer MCF-7 cells. Cell Physiol Biochem. 2015;35(2):722-8.

[3]. Chen J, et al. Calycosin suppresses breast cancer cell growth via ERβ-dependent regulation of IGF-1R, p38 MAPK and PI3K/Akt pathways. PLoS One. 2014 Mar 11;9(3):e91245.

[4]. Chen J, et al. Calycosin promotes proliferation of estrogen receptor-positive cells via estrogen receptors and ERK1/2 activation in vitro and in vivo. Cancer Lett. 2011 Sep 28;308(2):144-51.

Physicochemical properties of Calycosin

Density: 1.4 ± 0.1 g / cm3

Boiling point: 536.8 ± 50.0 ° C at 760 mmHg

Molecular formula: C16H12O5

Molecular weight: 284.263

Flash point: 205.7 ± 23.6 ° C

PSA：79.90000

Exact mass: 284.068481

LogP：2.41

Appearance: white to light yellow

Steam pressure: 0.0 ± 1.5 mmHg at 25 ° C

Refractive index: 1.669

Storage conditions: 2-8 ° C

Water solubility: methanol: soluble1mg / ml, clear, colorless

Safety informationof Calycosin

Symbol: ghs06

Signal word: danger

Hazard statement: h301

Warning statement: P301 + P310

Hazard Code (Europe): t

Risk Statement (Europe): 25

Safety Statement (Europe): 45

Dangerous Goods Transport Code: UN 3462 6.1 / pgiii

Calycosin customs

HS Code：2914509090

Chinese Overview：HS2914509090 ketones containing other oxygen groups Value added tax rate: 17.0%, tax rebate rate: 9.0%, regulatory conditions: no MFN tariff: 5.5%, ordinary tariff: 30.0%

Declaration elements: product name, component content, purpose, acetone declaration package

Calycosin literature

Thermal stability of kudzu root (Pueraria Radix) isoflavones as additives to beef patties.

J. Food Sci. Technol. 52(3) , 1578-85, (2015)

Kudzu root, Pueraria radix, extracts are a rich source of isoflavones. This study investigates the thermal stability of Puerar.

Calycosin orchestrates the functions of Danggui Buxue Tang, a Chinese herbal decoction composing of Astragali Radix and Angelica Sinensis Radix: An evaluation by using calycosin-knock out herbal extract.

J.Ethnopharmacol. 168 , 150-7, (2015)

K.Danggui Buxue Tang (DBT) is a classical Chinese herbal decoction containing two herbs, Astragali Radix (AR) and Angelicae Sinensis Radix (ASR), which serves as dietary supplement for treating women me...

J. Ethnopharmacol. 168 , 150-7, (2015)

Danggui Buxue Tang (DBT) is a classical Chinese herbal decoction containing two herbs, Astragali Radix (AR) and Angelicae Sinensis Radix (ASR), which serves as dietary supplement for treating women me...

Protective effects of calycosin against CCl4-induced liver injury with activation of FXR and STAT3 in mice.

Pharm. Res. 32(2) , 538-48, (2015)

Investigating the hepatoprotective effect of calycosin against acute liver injury in association with FXR activation and STAT3 phosphorylation.The acute liver injury model was established by intraperi...