Cov khoom

Chlorogenic acid muaj ntau yam kev ua haujlwm lom neeg.Kev tshawb fawb txog kev ua haujlwm lom neeg ntawm chlorogenic acid hauv kev tshawb fawb niaj hnub no tau nkag mus rau hauv ntau qhov chaw, xws li zaub mov, kev kho mob, tshuaj, kev lag luam tshuaj txhua hnub thiab lwm yam.Chlorogenic acid yog ib qho tseem ceeb ntawm cov khoom siv bioactive, uas muaj cov haujlwm ntawm cov kab mob tua kab mob, tshuaj tua kab mob, nce leukocyte, tiv thaiv daim siab thiab gallbladder, tiv thaiv qog, txo cov ntshav siab, txo cov ntshav lipid, tshem tawm cov dawb radicals thiab ua rau lub hauv paus paj hlwb.

Antibacterial thiab antiviral
Eucommia ulmoides chlorogenic acid muaj zog tiv thaiv kab mob thiab tiv thaiv kab mob, aucubin thiab nws cov polymers muaj cov nyhuv antibacterial pom tseeb, thiab aucubin muaj inhibitory cuam tshuam rau Gram-negative thiab zoo kab mob.Aucubin muaj cov nyhuv bacteriostatic thiab diuretic, thiab tuaj yeem txhawb kev kho qhov txhab;Aucubin thiab glucoside tuaj yeem tsim cov tshuaj tiv thaiv kab mob pom tseeb tom qab kab lis kev cai ua ntej, tab sis nws tsis muaj cov tshuaj tiv thaiv kab mob.Lub koom haum ntawm aging Medical Sciences, Aichi Medical University, tau lees paub tias cov tshuaj alkaline rho tawm los ntawm Eucommia ulmoides Oliv.Nws muaj peev xwm rhuav tshem tib neeg lub cev tiv thaiv kab mob.Cov tshuaj no tuaj yeem siv los tiv thaiv thiab kho AIDS.

Antioxidation
Chlorogenic acid yog ib qho zoo phenolic antioxidant.Nws lub peev xwm antioxidant muaj zog dua li caffeic acid, p-hydroxybenzoic acid, ferulic acid, syringic acid, butyl hydroxyanisole (BHA) thiab tocopherol.Chlorogenic acid muaj cov nyhuv antioxidant vim tias nws muaj qee yam ntawm R-OH radical, uas tuaj yeem tsim hydrogen radical nrog cov nyhuv antioxidant, txhawm rau tshem tawm cov haujlwm ntawm hydroxyl radical, superoxide anion thiab lwm yam dawb radicals, thiaj li tiv thaiv cov ntaub so ntswg los ntawm oxidative. kev puas tsuaj.

Dawb radical scavenging, anti-aging, anti musculoskeletal aging
Chlorogenic acid thiab nws cov derivatives muaj zog dawb radical scavenging nyhuv tshaj li ascorbic acid, caffeic acid thiab tocopherol (vitamin E), tuaj yeem tshem tawm DPPH dawb radical, hydroxyl dawb radical thiab superoxide anion dawb radical, thiab tseem tuaj yeem tiv thaiv oxidation ntawm tsawg-density. lipoprotein.Chlorogenic acid plays lub luag haujlwm tseem ceeb hauv kev tshem tawm cov dawb radicals zoo, tswj cov qauv thiab kev ua haujlwm ntawm lub cev hlwb, tiv thaiv thiab ncua qhov tshwm sim ntawm cov qog nqaij hlav thiab kev laus.Eucommia chlorogenic acid muaj cov khoom tshwj xeeb uas tuaj yeem txhawb kev sib txuas thiab decomposition ntawm collagen hauv tib neeg cov tawv nqaij, pob txha thiab cov leeg.Nws muaj kev ua haujlwm ntawm kev txhawb nqa cov metabolism thiab tiv thaiv kev poob qis.Nws tuaj yeem siv los tiv thaiv qhov poob ntawm cov pob txha thiab cov leeg los ntawm qhov chaw tsis muaj zog.Nyob rau tib lub sijhawm, nws pom tias Eucommia chlorogenic acid muaj qhov pom tseeb los tiv thaiv dawb radical nyhuv ob leeg hauv vivo thiab hauv vitro.

Inhibition ntawm mutation thiab antitumor
Cov kev sim tshuaj niaj hnub no tau ua pov thawj tias Eucommia ulmoides chlorogenic acid muaj cov teebmeem ntawm kev tiv thaiv kabmob thiab tiv thaiv kabmob.Cov kws tshawb fawb Nyij Pooj tau kawm txog antimutagenicity ntawm Eucommia ulmoides chlorogenic acid thiab pom tias cov nyhuv no muaj feem xyuam rau cov tshuaj tiv thaiv mutagenic xws li chlorogenic acid, qhia txog qhov tseem ceeb ntawm chlorogenic acid hauv kev tiv thaiv qog.
Polyphenols hauv zaub thiab txiv hmab txiv ntoo, xws li chlorogenic acid thiab caffeic acid, tuaj yeem inhibit qhov mutagenicity ntawm carcinogens aflatoxin B1 thiab benzo [a] - pyrene los ntawm inhibiting activated enzymes;Chlorogenic acid kuj tuaj yeem ua tiav kev tiv thaiv kab mob qog noj ntshav thiab tiv thaiv qog noj ntshav los ntawm kev txo qis kev siv cov carcinogens thiab lawv thauj hauv daim siab.Chlorogenic acid muaj qhov cuam tshuam loj heev rau kev mob qog nqaij hlav hauv plab, mob qog noj ntshav thiab mob qog noj ntshav.Nws raug suav hais tias yog ib qho tshuaj tiv thaiv zoo tiv thaiv kab mob qog noj ntshav.

Kev tiv thaiv zoo ntawm cov hlab plawv
Raws li cov dawb radical scavenger thiab antioxidant, chlorogenic acid tau raug pov thawj los ntawm ntau qhov kev sim.Qhov kev ua haujlwm lom neeg ntawm chlorogenic acid tuaj yeem tiv thaiv kab mob plawv.Isochlorogenic acid B muaj cov txiaj ntsig zoo ntawm kev txhawb nqa kev tso tawm ntawm prostacyclin (PGI2) thiab tiv thaiv platelet aggregation hauv nas;Tus nqi inhibition ntawm SRS-A tso tawm los ntawm cov tshuaj tiv thaiv rau guinea npua lub ntsws khib nyiab yog 62.3%.Isochlorogenic acid C kuj txhawb kev tso tawm ntawm PGI2.Tsis tas li ntawd, isochlorogenic acid B muaj zog inhibitory nyhuv ntawm platelet thromboxane biosynthesis thiab endothelin raug mob los ntawm hydrogen peroxide.

Hypotensive nyhuv
Nws tau raug pov thawj los ntawm ntau xyoo ntawm kev sim tshuaj uas Eucommia chlorogenic acid muaj cov nyhuv antihypertensive, ruaj khov nyhuv, tsis muaj tshuaj lom thiab tsis muaj kev phiv.Lub Tsev Kawm Ntawv Qib Siab Wisconsin tau pom tias cov khoom siv zoo ntawm Eucommia ulmoides ntsuab kom txo cov ntshav siab yog terpineol diglucoside, aucubin, chlorogenic acid, thiab Eucommia ulmoides chlorogenic acid polysaccharides.[5]

Lwm yam kev ua si lom neeg
Vim tias chlorogenic acid muaj qhov tshwj xeeb inhibitory cuam tshuam rau hyaluronic acid (HAase) thiab qabzib-6-phosphatase (gl-6-pase), chlorogenic acid muaj qee yam cuam tshuam rau qhov txhab kho, tawv nqaij noj qab haus huv thiab ntub dej, lubricating pob qij txha, tiv thaiv kev mob thiab cov kab mob. balance tswj cov ntshav qabzib hauv lub cev.Chlorogenic acid muaj zog inhibitory thiab tua cov teebmeem ntawm ntau yam kab mob thiab kab mob.Chlorogenic acid muaj cov tshuaj pharmacological ntawm kev txo cov ntshav siab, tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tiv thaiv kab mob, ua kom cov qe ntshav dawb, tiv thaiv ntshav qab zib, ua kom lub plab zom mov thiab txhawb kev zom zaub mov.Cov kev tshawb fawb tau pom tias qhov ncauj chlorogenic acid tuaj yeem ua rau muaj kev tso tawm ntawm cov kua tsib thiab muaj txiaj ntsig zoo rau lub gallbladder thiab tiv thaiv daim siab;Nws tseem tuaj yeem cuam tshuam cov hemolysis ntawm nas erythrocytes los ntawm H2O2.