Isoliquiritin Apioside
Ngwa nke Isoliquiritin Apioside
Isoliquiritin apioside, ihe dịpụrụ adịpụ na glycorrhizae redio rhome, belatara mmụba nke PMA na-ebute ọrụ MMP9 ma gbochie PMA na-ebute MAPK na NF-κ B.Isoliquitin apioside na-egbochi mbuso agha na angiogenesis nke mkpụrụ ndụ kansa na sel endothelial.
Aha nke Isoliquiritin Apioside
Aha Chinese:Isoliquiritin Apioside
Aha Bekee:(E) -3-[4-[(2S,3R,4S,5S,6R) -3-[(2S,3R,4R) -3,4-dihydroxy-4- (hydroxymethyl) oxolan-2-yl] oxy-4,5-dihydroxy-6- (hydroxymethyl) oxan-2-yl] oxyphenyl] -1- (2,4-dihydroxyphenyl) prop-2-en-1-otu.
Bioactivity nke Isoliquiritin Apioside
Nkọwa:isoliquitin apioside, ihe dịpụrụ adịpụ na glycorrhizae redio rhome, belatara mmụba nke PMA na-ebute ọrụ MMP9 ma gbochie PMA na-ebute MAPK na NF-κ B.Isoliquitin apioside na-egbochi mbuso agha na angiogenesis nke mkpụrụ ndụ kansa na sel endothelial.
Ejikọtara yaCụlọ akwụkwọ:ubi nyocha > > kansa
Ụzọ mgbama > > MAPK / ERK ụzọ mgbama > > p38 MAPK
Ụzọ mgbama > > metabolic enzyme / protease > > MMP
Ebumnuche:MMP9
NF-κB
p38 MAPK
Ọmụmụ in vitro:isorlicin nwere ike igbochi gelation MMP-9 nke mkpụrụ ndụ PMA butere HT1080 nke ọma.Isoglycyrrhizin apigenin na-ebelata mmụba nke mmepụta MMP-9 na sel HT1080 nke PMA kpatara, nwere ikike nke mgbochi metastasis na mgbochi angiogenesis na mkpụrụ ndụ tumor na mkpụrụ ndụ endothelial, na enweghị cytotoxicity [1].
Ntụaka:[1].Kim A1, et al.Isoliquiritin Apioside na-egbochi in vitro Invasiveness na Angiogenesis nke mkpụrụ ndụ kansa na mkpụrụ ndụ endothelial.Pharmacol ihu.2018 Disemba 10;9:1455 .
Njirimara physicochemical nke Isoliquiritin Apioside
Njupụta: 1.6 ± 0.1 g / cm3
Ebe esi mmiri: 901.0 ± 65.0 ° C na 760 mmHg
Usoro ihe omimi: c26h30o13
Ibu ibu: 550.509
Ebe ọkụ: 301.9 ± 27.8 Celsius C
Ọnụ ọgụgụ ziri ezi: 550.168640
PSA: 215.83000
Ihe ndekọ: 1.96
Nrụgide ikuku: 0.0 ± 0.3 mmHg na 25 Celsius
Ntụgharị ntụgharị: 1.709
Utu aha Bekee nke Isoliquiritin Apioside
2-Propen-1-otu,1- (2,4-dihydroxyphenyl) -3-[4-[[2-O-[(2S,3R,4R) -tetrahydro-3,4-dihydroxy-4- (hydroxymethyl). -2-furanyl] -β-D-glucopyranosyl] oxy] phenyl] -, (2E)
3-[(1E) -3- (2,4-Dihydroxyphenyl) -3-oxo-1-propen-1-yl] phenyl 2-O-[(2S,3R,4R) -3,4-dihydroxy-4 (hydroxymethyl) tetrahydro-2-furanyl]-β-D-glucopyranoside.
Neolicuroside
