Ophiopogonin D Cas No.945619-74-9
Ophiopogon Saponin D aha
Aha Bekee:(1β,3β,25R) -3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)] -6-deoxy-β-D-galactpyranoside
Bioactivity nke Ophiopogon Japonicus Saponin D
Nkọwa:Ophiopogon D bụ ihe okike C29 steroidal glycoside dịpụrụ adịpụ na tuber nke Ophiopogon japonicus.Ophiopogonin D bụ onye na-emepụta CYP2J3 nke na-eme ka CYP2J2 / eets na PPAR dị na sel endothelial vein umbilical (HUVECs) α Nkwupụta nke Ang II na-egbochi NF-κ B nuklea translocation, I κ B α Down Regulation2 + intracellular oke ibu na ịgbalite cytokines proinflammatory.A na-eji Ophiopogonin D agwọ ọnya na ọrịa obi ruo ọtụtụ puku afọ.
Otu dị mkpa
Ụzọ mgbama > > njem transmembrane > > ọwa calcium
Ogige nyocha > > ọrịa obi
Ụzọ mgbaàmà > > okirikiri cell / DNA mebiri >> PPAR
Ogige nyocha > > mbufụt / mgbochi
Ebumnuche
PPARA
NF-κB
Ca2+
Akwụkwọ ntụaka:[1].Wang L, et al.Homo-aro-cholestane, furostane na spirostane saponins sitere na tubers nke Ophiopogonjaponicus.Phytochemistry.2017 Eprel; 136: 125-132 .
[2].Huang X, et al.Ophiopogonin D na EET na-emezi nzaghachi mkpali Ang II kpatara site na ịgbalite PPARA na HUVECs.Akụkọ ihe mere eme nke Biochem Biophys Res Commun.2017 Ọgọst 19;490 (2): 123-133 .
Utu aha Bekee nke Ophiopogon saponin D
(1β,3β,25R) -3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)] -6-deoxy-β-D-galactopyranoside β-D-Galactopyranoside, (1β,3β,25R) -3-hydroxyspirost-5-en-1-yl O-6-deoxy-α-L-mannopyranosyl-(1- >2)-O-[β-D-xylopyranosyl-(1->3)]-6-deoxy-
(2S,3R,4R,5R,6S)-2-((2R,3R,4S,5S,6R)-5-hydroxy-2-(((4R,5'R,6R,6aR,6bS,8aS ,8bR,9S,10R,11aS,12aS,12bS)-4-hydroxy-5',6a,8a,9-tetramethyl-1,3,3',4,4',5,5',6,6a, 6b,6',7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2 '-pyran] -6-yl) oxy) -6-methyl-4-((2S,3R,4S,5R) -3,4,5-trihydroxytetrahydro-2H-pyran-2-yl) oxy) tetrahydro- 2H-pyran-3-yl) oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol.
Ophiopogonin D
Deacetylophiopogonin C
