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Hua

Obtusin

Whakaahuatanga Poto:

Ingoa noa: cassia

Ingoa Ingarihi: obtusin

Nama CAS: 70588-05-5

Taumaha rāpoi: 344.315

Ira kohua: 614 ± 0.4 MMG / 0.4 CMAT

Tātai rāpoi: C18H16O7

Ira Whakarewa: 614.9 ± 55.0 ° C i te 760 mmHg

MSDS: N/A

Ira Kohiko: 227.0 ± 25.0 ° C


Taipitopito Hua

Tohu Hua

Te whakamahi o Obtusin

Ko te Obtusin, mai i te purapura cassia, he tino whiriwhiri me te whakataetae whakataetae o te tangata monoamine oxidase-A (hmao-a), me te IC50 o 11.12 μ M. Ki te 6.15.Ka whai waahi a Obtusin ki te aukati i nga mate neurodegenerative, ina koa te awangawanga me te pouri.

Ingoa o Obtusin

Ingoa Ingarihi: Obtusin

Te koiora o Obtusin

Whakaahuatanga: Ko te obtusin no te kakano cassia.He tino whiriwhiri me te whakataetae whakataetae o te tangata monoamine oxidase-A (hmao-a), me te IC50 o 11.12 μ M. Ki te 6.15.Ka whai waahi a Obtusin ki te aukati i nga mate neurodegenerative, ina koa te awangawanga me te pouri.

Nga waahanga e pa ana: ara tohu > > ara tohu neural > > monoamine oxidase

Te mara rangahau > > mate neurological

Whāinga: IC50: 11.12 μ M (hMAO-A)[1] Ki: 6.15 (hMAO-A)[1]

Tohutoro: [1] Paudel P, et al.In Vitro and in Silico Human Monoamine Oxidase Inhibitory Potential of Anthraquinones, Naphthopyrones, and Naphthalenic Lactones from Cassia obtusifolia Linn Seeds.ACS Omega.2019 Hepetema 18;4(14):16139-16152.

Nga ahuatanga matū o Obtusin

Kiato: 1.4 ± 0.1 g / cm3

Kohuatanga: 614.9 ± 55.0 ° C i te 760 mmHg

Tātai rāpoi: c18h16o7

Taumaha rāpoi: 344.315

Ira Kohiko: 227.0 ± 25.0 ° C

Papatipu Tika: 344.089600

PSA:102.29000

RangitakiP:4.10

Te Peehanga Maamaa: 0.0 ± 1.8 mmHg i te 25 ° C

Taurangi Whakaata: 1.634

Nga korero haumaru o Obtusin

Waehere Tikanga: 2914690090

Tuhituhi: Cameron, Donald W;Feutrill, Geoffrey I.;Gamble, Glenn B.;Stavrakis, John Tetrahedron Letters, 1986, vol.27, # 41 p.4999 - 5002

Obtusin Customs

Waehere Tikanga: 2914690090

Tirohanga Hainamana: Tirohanga Hainamana

Whakarāpopototanga:2914690090 atu quinones. Tikanga tirotiro:Karekau

Ingoa Ingoa o Nga Tikanga

9,10-Anthracenedione, 1,7-dihydroxy-2,3,8-trimethoxy-6-methyl-

1,7-dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione

1,7-Dihydroxy-2,3,8-trimethoxy-6-methyl-9,10-anthraquinone

Mana Kounga Hua

1. I hokona e te kamupene te irirangi autō karihi (Bruker 400MHz), te inenga o te wahanga wai (LCMS), te irirangi papatipu hau (GCMs), te inenga papatipu (Wai SQD), te maha o nga tātaritanga aunoa o nga chromatograph wai mahi teitei, nga chromatographs wai whakarite, etc .

2. Ka mau tonu te mahi tahi a te kamupene me te whakapiri atu ki nga whare rangahau pūtaiao penei i te Shanghai Institute mo te whakahaere tarukino, Nanjing biomedical public service platform me te tātari me te pokapū whakamatautau o Shanghai Pharmaceutical Industry Research Institute.

3. Kei te kaha te kamupene ki te kawe i nga tiwhikete whakamatautau taiwhanga tuatoru, me te tumanako ka whiwhi Tiwhikete Whakamana Taiwhanga CNA i te tau 2021.


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