Paeoniflorin CAS No. 23180-57-6
Zambiri Zofunikira
Imadziwikanso kuti paeoniflorin, ndi pinane monoterpene bitter glycoside yomwe ili kutali ndi peony yofiira ndi peony yoyera.Ndi hygroscopic amorphous ufa.Imapezeka pamizu ya Paeonia, peony, peony yofiirira ndi zomera zina za Ranunculaceae.Kawopsedwe ka kristalo uyu ndi wotsika kwambiri.
[dzina lamankhwala]5beta- [(Benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1alpha(2H)-yl-beta-D-glucopyranoside
[chilinganizo cha maselo]C23H28O11
【CASAyi】23180-57-6
Kuyera: pamwamba pa 98%, njira yodziwira: HPLC.
[gwero]mizu ya Paeonia albiflora pall, P. suffrsticosa Andr, P. delarayi Franch, chomera cha Ranunculaceae, zomwe zili mu radix paeoniae Rubr ndizopamwamba kwambiri.
[Mafotokozedwe]10%, 20%, 30%, 50%, 90%, 98%
[AntchitoIchopangira ] Total glucosides of Paeonia (TGP) ndi dzina lambiri la paeoniflorin, hydroxy paeoniflorin, paeoniflorin, albiflorin ndi benzoyl paeoniflorin, lomwe limatchedwa TGP mwachidule.
Thupi ndi mankhwala katundu
Ndi hygroscopic amorphous Tan powder (90% yachoka ufa woyera) [α] 16D-12.8. (C = 4.6, methanol), tetraacetate ndi kristalo wopanda mtundu wa acicular, malo osungunuka: 196 ℃.Paeoniflorin ndi yokhazikika m'malo okhala acidic (pH 2 ~ 6) komanso osakhazikika m'malo amchere.
Kutsimikiza Kwazinthu
Nthawi zambiri, njira 1 ndi 2 zitha kugwiritsidwanso ntchito pozindikira.Njira 1 imagwiritsidwa ntchito bwino popanga zinthu zambiri, zomwe zingathandize ogwira ntchito kuweruza bwino kuyera kwazinthu.Zomwe zimatchulidwa zimakhala zosavuta kuwola pambuyo pa kusungunuka.
1.Inatsimikiziridwa ndi chromatography yamadzimadzi yapamwamba kwambiri (Zowonjezera VI d).Maonekedwe a chromatographic ndi kuyenerera kwadongosolo adayesedwa ndi Octadecyl silane yomangika silika gel ngati filler;Acetonitrile-0.1% yankho la phosphoric acid (14:86) linagwiritsidwa ntchito ngati gawo la mafoni;Kutalika kwa mawonekedwe ndi 230nm.Chiwerengero cha mbale zongoyerekeza zowerengedwa molingana ndi nsonga ya paeoniflorin sichiyenera kukhala yochepera 2000. Kukonzekera yankho lachidziwitso: kuyeza molondola kuchuluka koyenera kwa yankho la paeoniflorin ndikuwonjezera methanol kukonzekera 60% paeoniflorin pa 1ml μ G yankho.
2.Kupititsa patsogolo njira yotsimikizika ya paeoniflorin mu Radix Paeoniae Alba.Njira: Njira zaku China Pharmacopoeia ndi njira zowongoleredwa zidafaniziridwa.Gawo loyendayenda linali madzi a methanol (30:70) ndipo kutalika kwa mawonekedwe kunali 230nm.zotsatira;Ubale wa mzere wa njirayi ndi wabwino (r = 0.9995).Kuchira kwapakati ndi 101.518% ndipo RSD ndi 1.682%.Kutsiliza: njira yabwino ndi yosavuta komanso yolondola, yomwe ingachepetse kawopsedwe wa zosungunulira za organic kwa anthu ndi kuipitsidwa kwa chilengedwe, ndikupereka umboni wotsimikizira za paeoniflorin pochita.
Njira Yotsimikizira
Kutsimikiza kwa paeoniflorin ndi HPLC
Kuchuluka kwa ntchito:njira imeneyi amagwiritsa HPLC kudziwa zili paeoniflorin mu Guizhi Fuling mapiritsi.
Njirayi ndi yoyenera mapiritsi a Guizhi Fuling.
Njira mfundo:ikani chitsanzo choyesera mu botolo la conical, onjezerani mlingo woyenerera wa ethanol wosungunuka kuti akupanga m'zigawo, kuziziritsa, kugwedeza bwino, kusefa, kusefa, filtrate imalowa m'madzi amadzimadzi a chromatograph kwa chromatographic kupatukana, gwiritsani ntchito chowunikira cha ultraviolet kuti muzindikire kuyamwa kwa paeoniflorin pamtunda wa 230nm, ndikuwerengera zomwe zili.
