Platycodin D CAS No. 58479-68-8
Essential Information
Extraction source: Platycodon grandiflorum (Jacq.) A.DC. Dry roots.
Detection mode: HPLC ≥ 98%.
Specifications: 20mg, 50mg, 100mg, 500mg, 1g (can be packaged according to customer requirements).
Character: It is white crystalline powder.
Purpose: Used for content determination.
Loss on drying: ≤ 2%
Purity: 95%, 98%, 99%
Analytical Method: HPLC-DAD ＾ or / and ＾ HPLC-ELSD
Identification methods: mass spectrometry (mass), nuclear magnetic resonance (NMR)
Storage: sealed and protected from light, - 20 ℃.
Precautions: This product should be stored at low temperature and dry. Special products should be stored under nitrogen. If it is not stored for a long time, the content will be reduced.
Validity: 2 years
It can meet a large number of demands above gram level. Please consult for details.
Bioactivity Of Platycodin D
Description: platycodin D is a saponin compound isolated from orange stalk, which is AMPK α It has anti obesity activity.
Related Categories: signaling pathway > > epigenetics > > AMPK
Signal pathway > > PI3K / Akt / mTOR signal pathway > > AMPK
Research field > > metabolic diseases
Target: AMPK α [1]
References: [1] Kim HL, et al. Platycodin D, a novel activator of AMP-activated protein kinase, attenuates obesity in db/db mice via regulation of adipogenesis and thermogenesis. Phytomedicine. 2019 Jan; 52:254-263.
Physicochemical Properties of Platycodin D
Density: 1.6 ± 0.1 g / cm3
Molecular formula: c57h92o28
Molecular weight: 1225.324
Exact mass: 1224.577515
PSA: 453.28000
LogP: -0.69
Refractive index: 1.659
