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Ibicuruzwa

Acide ya Chlorogenic CAS No.327-97-9

Ibisobanuro bigufi:

Acide ya Chlorogenic ni ifumbire mvaruganda hamwe na formula c16h18o9.Nibimwe mubintu nyamukuru birwanya antibacterial na antiviral bikora imiti ikora ubuki.Hemihydrate ni kirisiti ya kirisiti (amazi).110 ℃ ihinduka ibice bidafite imbaraga.Amashanyarazi muri 25 ℃ amazi ni 4%, kandi gukomera mumazi ashyushye ni byinshi.Byoroshye gushonga muri Ethanol na acetone, gushonga gato cyane muri Ethyl acetate.


Ibicuruzwa birambuye

Ibicuruzwa

Amakuru y'ingenzi

Acide ya Chlorogenic ifite ingaruka nyinshi za antibacterial, ariko irashobora kudakorwa na proteyine muri vivo.Kimwe na acide cafeque, inshinge zo mu kanwa cyangwa intraperitoneal zirashobora kunoza imitekerereze yimbeba.Irashobora kongera amara ya peristalisite yimbeba nimbeba hamwe nuburemere bwa nyababyeyi.Ifite cholagogic kandi irashobora kongera ururenda rwimbeba.Ifite ubukangurambaga ku bantu.Asima na dermatite birashobora kubaho nyuma yo guhumeka umukungugu wibimera birimo iki gicuruzwa.

Izina ry'Ubushinwa: Acide Chlorogenic

Izina ry'amahanga: Acide Chlorogenic

Imiti yimiti: C16H18O9

Uburemere bwa molekuline: 354.31

URUBANZA No.:327-97-9

Ingingo yo gushonga: 208 ℃;

Ingingo yo guteka: 665 ℃;

Ubucucike: 1,65 g / cm ³

Ingingo ya Flash: 245.5 ℃

Igipimo cyerekana: - 37 °

Amakuru yuburozi

Uburozi bukabije: igipimo cyica byibuze (imbeba, cavit yo munda) 4000mg / kg

Amakuru y’ibidukikije

Izindi ngaruka mbi: ibintu bishobora kwangiza ibidukikije, kandi hagomba kwitabwaho cyane umubiri wamazi.

Inkomoko

E. , Polygonaceae igihingwa kibitse ibyatsi byose, Igiti cya Rubiaceae tarpaulin ibyatsi byose, ibihingwa byubuki capsule Zhai Ibyatsi Byose.Amababi y'ibijumba mumuryango Convolvulaceae.Imbuto za kawa ntoya yimbuto, ikawa yimbuto yo hagati hamwe nikawa nini yimbuto.Amababi n'imizi ya Arctium lappa

Gukoresha Acide ya Chlorogene

Acide Chlorogenic ifite ibikorwa byinshi byibinyabuzima.Ubushakashatsi ku bikorwa by’ibinyabuzima bya aside ya chlorogene mu bumenyi bugezweho bwinjiye mu bice byinshi, nk'ibiribwa, ubuvuzi, ubuvuzi, inganda z’imiti ya buri munsi n'ibindi.Acide Chlorogenic ni ikintu cyingenzi cya bioactive, gifite imirimo ya antibacterial, antiviral, kongera leukocyte, kurinda umwijima na gallbladder, anti-tumor, kugabanya umuvuduko wamaraso, kugabanya lipide yamaraso, gusohora radicals yubusa no gushimisha sisitemu yo hagati.

Antibacterial na antiviral
Eucommia ulmoides chlorogenic aside ifite antibacterial na anti-inflammatory, aucubin na polymers zayo zigira ingaruka zigaragara za antibacterial, kandi aucubin igira ingaruka mbi kuri bacteri za Gram-mbi kandi nziza.Aucubin ifite bacteriostatike na diuretique, kandi irashobora gukiza ibikomere;Aucubin na glucoside birashobora kandi gutanga ingaruka zigaragara nyuma yumuco, ariko ntabwo bifite imikorere ya virusi.Ikigo cy’ubuvuzi cya kera cy’ubuvuzi, kaminuza y’ubuvuzi ya Aichi, cyemeje ko ibintu bya alkaline byakuwe muri Eucommia ulmoides Oliv.Ifite ubushobozi bwo gusenya virusi yumubiri wumuntu.Iyi ngingo irashobora gukoreshwa mukurinda no kuvura sida.

Antioxyde
Acide Chlorogenic ni antioxydants ya fenolike ikora.Ubushobozi bwa antioxydeant bukomeye kuruta aside ya cafeque, p-hydroxybenzoic aside, aside ferulic, aside syringic, butyl hydroxyanisole (BHA) na tocopherol.Acide Chlorogenic ifite antioxydeant kuko irimo urugero runaka rwa R-OH radical, ishobora gukora hydrogène radical hamwe na antioxydeant, kugirango ikureho ibikorwa bya hydroxyl radical, anero ya superoxide nizindi radicals yubuntu, kugirango irinde ingirangingo okiside. ibyangiritse.

Ubusa radical scavenging, anti-gusaza, anti musculoskeletal gusaza
Acide ya Chlorogenic n'ibiyikomokaho bifite imbaraga zikomeye zo gusiba radical aside aside, acide cafeque na tocopherol (vitamine E), irashobora gukuramo neza DPPH radical radical, hydroxyl free radical na superoxide anion yubusa, kandi irashobora no kubuza okiside yubucucike buke. lipoprotein.Acide Chlorogenic igira uruhare runini mugusiba neza radicals yubuntu, kugumana imiterere nimikorere isanzwe yingirangingo z'umubiri, kwirinda no gutinda kubaho kwa mutation yibibyimba no gusaza.Eucommia chlorogenic aside irimo ibintu byihariye bishobora guteza imbere synthesis no kubora kwa kolagen mu ruhu rwabantu, amagufwa n'imitsi.Ifite umurimo wo guteza imbere metabolism no gukumira kugabanuka.Irashobora gukoreshwa mukurinda kugabanuka kw'amagufwa n'imitsi biterwa n'uburemere bw'ikirere.Muri icyo gihe, usanga aside Eucommia chlorogenic ifite ingaruka zigaragara zo kurwanya radical yubusa haba muri vivo ndetse no muri vitro.

Kubuza mutation na antitumor
Ubushakashatsi bwa farumasi bugezweho bwerekanye ko Eucommia ulmoides chlorogenic aside ifite ingaruka zo kurwanya kanseri no kurwanya kanseri.Intiti z'Abayapani zakoze ubushakashatsi kuri antimutagenicity ya Eucommia ulmoides chlorogenic aside basanga iyi ngaruka ifitanye isano na anti-mutagenic nka aside ya chlorogene, igaragaza akamaro gakomeye ka aside ya chlorogene mu gukumira ibibyimba.
Polifenole mu mboga n'imbuto, nka aside ya chlorogene na aside ya cafeque, irashobora kubuza mutagenicite ya kanseri aflatoxine B1 na benzo [a] - pyrene mu guhagarika imisemburo ikora;Acide ya Chlorogenic irashobora kandi kugera ku ngaruka zo kurwanya kanseri no kurwanya kanseri mu kugabanya ikoreshwa rya kanseri no kuyitwara mu mwijima.Acide Chlorogenic igira ingaruka zikomeye zo kubuza kanseri yibara, kanseri y'umwijima na kanseri yo mu muhogo.Bifatwa nkigikoresho cyiza cyo kurinda kanseri.

Ingaruka zo gukingira sisitemu yumutima
Nka radical scavenger yubusa na antioxydeant, aside ya chlorogeneque yerekanwe nubushakashatsi bwinshi.Iki gikorwa cyibinyabuzima cya aside ya chlorogene irashobora kurinda sisitemu yumutima.Acide Isochlorogenic B igira ingaruka zikomeye mu guteza imbere irekurwa rya prostacyclin (PGI2) hamwe no kurwanya anti-platelet mu mbeba;Igipimo cyo kubuza SRS-Irekurwa ryatewe na antibody kuri guinea ingurube y’ibihaha yari 62.3%.Acide Isochlorogenic C nayo yateje imbere irekurwa rya PGI2.Byongeye kandi, aside isochlorogenic B ifite ingaruka zikomeye zo kubuza platine thromboxane biosynthesis no gukomeretsa endothelin iterwa na hydrogen peroxide.

Ingaruka ya hypotensive
Byagaragajwe n’imyaka myinshi y’ibizamini by’amavuriro ko aside Eucommia chlorogenic ifite ingaruka zigaragara zo kurwanya antivypertensique, ingaruka zo kuvura zihamye, zidafite uburozi kandi nta ngaruka mbi.Kaminuza ya Wisconsin yasanze ibice byingenzi bigize Eucommia ulmoides icyatsi kugirango igabanye umuvuduko wamaraso ni terpineol diglucoside, aucubin, aside chlorogene, na Eucommia ulmoides chlorogenic aside polysaccharide.[5]

Ibindi bikorwa byibinyabuzima
Kubera ko aside ya chlorogène igira ingaruka zidasanzwe zo kubuza aside hyaluronike (HAase) na glucose-6-fosifata (gl-6-pase), aside ya chlorogene igira ingaruka runaka mugukiza ibikomere, ubuzima bwuruhu no gutose, guhuza amavuta, kwirinda gutwika no kuringaniza kugenzura amaraso glucose mumubiri.Acide Chlorogenic ifite imbaraga zo kubuza no kwica indwara zitandukanye na virusi.Acide Chlorogenic ifite ingaruka za farumasi zo kugabanya umuvuduko wamaraso, antibacterial, antiviral, anti-inflammatory, kongera selile yera, kwirinda diyabete, kongera umuvuduko wa gastrointestinal no guteza imbere ururenda.Ubushakashatsi bwerekanye ko aside ya chlorogene yo mu kanwa ishobora gukurura cyane ururenda rwa bile kandi ikagira ingaruka zo kugirira umwijima no kurinda umwijima;Irashobora kandi guhagarika neza hemolysis ya imbeba erythrocytes yatewe na H2O2.


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