Esculin;Aesculin;Esculoside;Bicolorin;Escosyl
Ikoreshwa rya Esculin
Bioflavonoide, antioxydeant, iteza imbere vitamine C.
Igikorwa cya Esculin
1. Kurwanya inflammatory na analgesia: imbeba zatewe inshinge 10mg / kg.Carrageenan yatewe, dextrose iterwa, serotonine yatewe na histamine yatewe na "arthritis" yagize ingaruka zo kubuza, kandi ubukana bwa inhibitori bwari 35,28,20,8% buri kimwe Biravugwa kandi ko bugira ingaruka mbi kuri arthrite ya formaldehyde, ariko ingaruka ni intege nke kurenza iya karrageenan iterwa na rubagimpande;Kubuza arthritis dextran ntabwo bigaragara Birashobora kubuza ishingwa rya granuloma mu mbeba (uburyo bwumupira w ipamba), erythema reaction iterwa nimirasire ya ultraviolet inyuma yingurube, hamwe no kwiyongera kwa capillary capillary yatewe na histamine Ifite intege nke zo gusesengura. .
2. Ingaruka ku mubare w'inkari no gusohora aside irike: inzira zitandukanye z'ubuyobozi zirashobora kongera aside irike mu mbeba n'inkwavu, kandi nta ngaruka ya diuretique ifata ku mbeba zisanzwe, ariko bigira ingaruka zikomeye ku mbeba.
3.Ibindi: antibacterial, anticoagulant no kubuza reddase ya aldose mumurongo wimbeba.
Izina rya Esculin
Izina ry'icyongereza: esculin
Izina ry'Ubushinwa: Heptachlor hemihydrate |heptachlor hemihydrate |6- （β- D-glucopyranoxy) - 7-hydroxy-2h-1-benzofuran-2-umwe |aescin |ifarashi yigituba bark glycoside |igituba igituba glycoside Umwuka wibibabi birindwi Aescin |Qiyeling |igituba igituba glycoside |aescin |6 - (beta-d-glucopyranoxy) - 7-hydroxy-2h-1-benzofuran-2-imwe
Bioactivite ya Esculine
Ibisobanuro: esculine ni fluorescent coumarin glucoside, nikintu cyiza cyibara ryatsi.Esculine itezimbere ubumuga bwo kutamenya mubushakashatsi bwa diabete ya diabete (DN) ikoresheje inzira ya MAPK yerekana inzira, kandi ikora antioxydeant ningaruka zo kurwanya inflammatory.
Ibyiciro bifitanye isano: urwego rwubushakashatsi >> kanseri
Intego: p38 MAPK
Reba:
[1].Knox K, n'abandi.Coumarin Glucoside, Esculin, Yerekana Impinduka Zihuse mu muvuduko wa Phloem-Transport mu gusubiza ibibazo by’ibidukikije.Tera Physiol.2018 Ukwakira;178 (2): 795-807.
[2].Indirimbo Y, n'abandi.Esculin ikuraho ubumuga bwo kutamenya muri nepropatique ya diyabete yubushakashatsi kandi itera guhagarika umutima no kurwanya anti-inflammatory binyuze munzira ya MAPK.Mol Med Rep. 2018 Gicurasi;17 (5): 7395-7402.
Ibintu bya fiziki ya Himiki ya Esculine
Ubucucike: 1,7 ± 0.1 g / cm3
Ingingo yo guteka: 697.7 ± 55.0 ° C kuri 760 mmHg
Ingingo yo gushonga: 203 ° C.
Inzira ya molekulari: c15h16o9
Uburemere bwa molekuline: 358.297
Ingingo ya Flash: 262.8 ± 25.0 ° C.
Misa nyayo: 358.089996
PSA: 358.089996
LogP: -1.52
Kugaragara: ifu ya cream
Umuvuduko wamazi: 0.0 ± 2,3 mmHg kuri 25 ° C.
Ironderero: 1.689
Ububiko
1 Bika mububiko bukonje, bwumye kandi buhumeka neza.Irinde gucana nubushyuhe.Irinde izuba ryinshi.Gufunga ibicuruzwa.Igomba kubikwa ukwayo na acide hamwe n’imiti iribwa, kandi ububiko buvanze ntibwemerewe.Ahantu ho guhunika hagomba kuba hafite ibikoresho bikwiye kugirango bitemba.
2. Argon yuzuye ububiko bwa kashe
Igihagararo: koresha kandi ubike ukurikije ibisobanuro utabora kandi wirinde guhura na oxyde
Amazi meza: icyitegererezo
Imiterere ya molekulari
1. Indangantege ya Molar: 77.35
2. Ingano ya Molar (cm3 / mol): 202.6
3. Ijwi ryihariye rya Isotonic (90.2k): 628.5
4. Ubushyuhe bwo hejuru (dyne / cm): 92.6
5. Polarizability (10-24cm3): 30.66
Amakuru yumutekano wa Esculin
Kode ya Hazard (Uburayi): F, C, Xi
Ibisobanuro (Europe): R11
Itangazo ryumutekano (Uburayi): s26-s36 / 37/39-s45-s24 / 25
Kode yo gutwara ibicuruzwa biteje akaga: UN 2924 3 / PG 2
Wgk Ubudage: 3
RTECS Oya: dj3085000
Kode ya gasutamo: 2942000000
Gasutamo ya Esculin
Kode ya gasutamo: 2942000000
Icyongereza Alias wo muri Esculin
Crataegin
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside
EINECS 208-517-5
vitamine2
Enallachrome
Esculetin 6-β-D-glucoside
POLYDROM
Bicolorin
Esculetin 6-O-glucoside
Polychrom
7-Hydroxy-2-oxo-2H-chromen-6-yl-β-D-glucopyranoside
BICOLOIN
7-Hydroxycoumarin-6-yl β-D-Glucopyranoside Sesquihydrate
Esculin
7-Hydroxy-6 - {[(2S, 3R, 4S, 5S, 6R) -3,4,5-trihydroxy-6- (hydroxymethyl) tetrahydro-2H-pyran-2-yl] oxy} -2H-chromen- 2-umwe
6- (β-D-Glucopyranosyloxy) -7-hydroxy-2H-1-benzopyran-2-imwe
Esculetin 6-bD-glucoside
2H-1-Benzopyran-2-imwe, 6- (β-D-glucopyranosyloxy) -7-hydroxy-
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside hydrate (1: 1)
Aesculin
MFCD00006879
Esculetin-6-O-glucoside
2H-1-Benzopyran-2-imwe, 6- (β-D-glucopyranosyloxy) -7-hydroxy-, hydrate (1: 1)
Escosyl
