Esculin;Aesculin;Esculoside;Bicolorin;Escosyl
Tšebeliso ea Esculin
Li-bioflavonoids, antioxidant, li khothalletsa litaba tsa vithamine C.
Ketso ea Esculin
1. Anti-inflammatory le analgesia: likhoto li ne li kenngoa ka intraperitoneally ka 10mg / kg.Carrageenan induced, dextrose induced, serotonin induced le histamine induced "ramatiki" e bile le litlamorao tsa inhibitory, 'me inhibitory inhibitory intents 35,28,20,8% ka ho latellana Ho boetse ho tlalehoa hore e na le phello e thibelang ho ramatiki e bakoang ke formaldehyde, empa phello ke. e fokolang ho feta ea ramatiki e bakoang ke carrageenan;Thibelo ea ramatiki ea dextran ha e totobetse E ka thibela ho thehoa ha granuloma ho likhoto (mokhoa oa bolo ea k'hothone), karabelo ea erythema e bakoang ke mahlaseli a kotsi a mokokotlo oa likolobe, le ho eketseha ha capillary permeability e bakoang ke histamine E na le phello e fokolang ea analgesic. .
2. Phello ea molumo oa moroto le ho tsoa ha uric acid: litsela tse fapaneng tsa tsamaiso li ka ntlafatsa ho tsoa ha uric acid ho likhoto le mebutlanyana, 'me ha li na phello ea diuretic ho likhoto tse tloaelehileng, empa li na le phello e kholo ea diuretic ho litoeba.
3.Ba bang: antibacterial, anticoagulant le inhibiting aldose reductase ka lense ea rat.
Lebitso la Esculin
Lebitso la Senyesemane :esculin
Lebitso la Sechaena: Heptachlor hemihydrate |heptachlor hemihydrate |6-( β- D-glucopyranoxy) - 7-hydroxy-2h-1-benzofuran-2-one |aescin |pere ea chestnut bark glycoside |chestnut makhapetla glycoside Seven lekhasi moea Aescin |Qeling |chestnut makhapetla glycoside |aescin |6 - (beta-d-glucopyranoxy) - 7-hydroxy-2h-1-benzofuran-2-one
Bioactivity ea Esculin
Tlhaloso: esculin ke fluorescent coumarin glucoside, e leng karolo e sebetsang ea makhapetla a bohlooho.Esculin e ntlafatsa ho senyeha ha kelello ho liteko tsa lefu la tsoekere (DN) ka tsela ea pontšo ea MAPK, 'me e fana ka khatello ea kelello ea antioxidant le liphello tse khahlanong le ho ruruha.
Likarolo tse amanang le tsona: sebaka sa lipatlisiso> > kankere
Sepheo: p38 MAPK
Referense:
[1].Knox K, le ba bang.Coumarin Glucoside, Esculin, e Senola Liphetoho tse Potlakileng ho Phloem-Sepalangoang Lebelo la ho Araba Maemo a Tikoloho.Semela Physiol.2018 Oct;178(2):795-807.
[2].Pina ea Y, le ba bang.Esculin e ntlafatsa ho senyeha ha kelello ho nephropathy ea liteko tsa lefu la tsoekere mme e baka khatello ea maikutlo e khahlanong le oxidative le litlamorao tse khahlanong le ho ruruha ka tsela ea MAPK.Mol Med Rep. 2018 May;17(5):7395-7402.
Thepa ea Physicochemical ea Esculin
Boima: 1.7 ± 0.1 g / cm3
Ntho e Belang: 697.7 ± 55.0 ° C ho 760 mmHg
Sebaka se qhibilihang: 203 ° C
Foromo ea molek'hule: c15h16o9
Boima ba 'mele: 358.297
Flash Point: 262.8 ± 25.0 ° C
Boima bo nepahetseng: 358.089996
PSA:358.089996
LogP: -1.52
Ponahalo: phofo ea tranelate
Khatello ea Mouoane: 0.0 ± 2.3 mmHg ho 25 ° C
Index ea Refractive: 1.689
Maemo a polokelo
1 Boloka sebakeng sa polokelo se pholileng, se omeletseng le se nang le moea o motle.Qoba hole le mehloli ea mocheso le mocheso.Sireletsa letsatsing le tobileng.Ho tiisa sephutheloana.E tla bolokoa ka thoko ho li-acids le lik'hemik'hale tse jeoang, 'me polokelo e tsoakiloeng e ke ke ea lumelloa.Sebaka sa polokelo se tla hlomelloa ka lisebelisoa tse loketseng ho thibela ho lutla.
2. Argon e tletse polokelo e tiisitsoeng
Stability: Sebelisa le ho boloka ho latela litlhaloso ntle le ho bola le ho qoba ho kopana le oxides
Ho qhibiliha ha metsi: ho qhibiliha ha mohlala
Sebopeho sa limolek'hule
1. Molar refractive index: 77.35
2. Molumo oa Molar (cm3 / mol): 202.6
3. Molumo o khethehileng oa Isotonic (90.2k): 628.5
4. Khatello ea sefahleho (dyne / cm): 92.6
5. Polarizability (10-24cm3): 30.66
Litaba tsa Tšireletseho ea Esculin
Khoutu ea kotsi (Europe): F, C, Xi
Tlaleho ea Kotsi (Yuropa): R11
Polelo ea Tšireletseho (Yuropa): s26-s36 / 37 / 39-s45-s24 / 25
Khoutu ea Lipalangoang ea thepa e kotsi: UN 2924 3 / PG 2
Wgk Jeremane: 3
Nomoro ea RTECS: dj3085000
Meetlo Code: 2942000000
Mekhoa ea Esculin
Meetlo Code:2942000000
Lebitso la Senyesemane la Esculin
Crataegin
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside
EINECS 208-517-5
vithaminec2
Enallachrome
Esculetin 6-β-D-glucoside
POLYDROME
Bicolorin
Esculetin 6-O-glucoside
Polychrom
7-Hydroxy-2-oxo-2H-chromen-6-yl-β-D-glucopyranoside
KHOLOANE
7-Hydroxycoumarin-6-yl β-D-Glucopyranoside Sesquihydrate
Esculin
7-Hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-2H-chromen- 2-nngwe
6-(β-D-Glucopyranosyloxy) -7-hydroxy-2H-1-benzopyran-2-one
Esculetin 6-bD-glucoside
2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy) -7-hydroxy-
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside hydrate (1:1)
Aesculin
MFCD00006879
Esculetin-6-O-glucoside
2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy) -7-hydroxy-, hydrate (1:1)
Escosyl
