Synephrine (oxedrine) is derived from citrus plants α- Adrenergic and β- Adrenergic agonists have sympathomic and structural similarities with ephedra and ephedrine alkaloids.
Name Of Synephrine
English Name: synephrine
Chinese alias: deoxyepinephrine | simforine | DL deoxyepinephrine | 1-p-hydroxyphenyl-2-methylaminoethanol | cinephrine | 1 - (4-hydroxyphenyl) - 2 - (methylamino) ethanol
Bioactivity Of Synephrine
Description: synephrine (oxedrine) is derived from citrus plants α- Adrenergic and β- Adrenergic agonists have sympathomic and structural similarities with ephedra and ephedrine alkaloids.
Relevant Categories: α- adrenergic and β- adrenergic
In Vivo Study: adrenaline (1mg / kg; oral gavage; lasting for 8 days; PVL and BDL rats) significantly improved the hyperkinetic state of PVL and BDL rats. PVL and BDL rats significantly decreased portal vein pressure, portal vein branch bleeding flow and cardiac index, while adrenaline treatment increased mean arterial pressure and systemic and portal vein vascular resistance . Animal model: Rats with portal vein ligation (PVL) or bile duct ligation (BDL)  dose: 1 mg / kg every 12 hours: oral gavage; Results on day 8: PVL and BDL rats had significantly decreased portal vein pressure, portal branch blood flow and cardiac index, and increased mean arterial pressure and systemic and portal vein resistance
References: 1] Thomas JE, et al. STEMI in a 24-year-old man after use of a synephrine-containing dietary supplement: a case report and review of the literature. Tex Heart Inst J. 2009; 36(6):586-90.
. Huang YT, et al. Hemodynamic effects of synephrine treatment in portal hypertensive rats. Jpn J Pharmacol. 2001 Feb; 85(2):183-8.
Physicochemical Properties Of Simephrine
Density: 1.2 ± 0.1 g / cm3
Boiling Point: 341.1 ± 27.0 ° C at 760 mmHg
Melting point: 187 ° C (Dec.) (lit.)
Molecular Formula: C9H13NO2
Molecular Weight: 167.205
Flash point: 163.4 ± 14.3 ° C
Exact mass: 167.094635
Appearance: off white to beige powder
Steam Pressure: 0.0 ± 0.8 mmHg at 25 ° C
Refractive Index: 1.572
Storage Conditions: This product should be sealed and stored.
Safety Information Of Synflynn
Signal word: warning
Hazard statement: h315-h319-h335
Warning statement: p261-p305 + P351 + P338
Personal protective equipment: dust mask type N95 (US); Eyeshields; Gloves
Hazard code (Europe): Xi: iritant;
Risk statement (Europe): R36 / 37 / 38
Safety statement (Europe): s26-s36
Transport code of dangerous goods: nonh for all modes of transport
RTECS No.: do7350000
Customs Code: 2922199090
Results of citrus aurantium L.
Customs Code: 29225090
Chinese overview: 29225090 Other amino alcohol phenols, amino acid phenols and other oxygenated amino compounds VAT rate: 17.0% Tax rebate rate: 13.0% Regulatory conditions: ab. MFN tariff: 6.5% General tariff: 30.0%
Declaration Elements: product name, composition, content, purpose, chroma of ethanolamine and its salt shall be reported, and packaging of ethanolamine and its salt shall be reported
Supervision conditions: A. customs clearance form for Inbound Goods B. customs clearance form for outbound goods
Inspection And Quarantine: R. sanitary supervision and inspection of imported food S. sanitary supervision and inspection of exported food
Summary:2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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English Alias Of Synephrine
Benzenemethanol, 4-hydroxy-α-[(methylamino)methyl]-, (αR)-