Vitexin; Apigenin8-C-glucoside CAS No. 3681-93-4

Short Description:

Vitexin is a natural flavonoid extracted from Vitex leaves and Vitex seeds. However, because the plant Vitex is still in the wild state, it is common in southern mountainous areas but grows scattered. There are few artificial Vitex, and there are almost no real large-scale cultivation of Vitex. The leaves and seeds of Vitex trifolia collected by conventional Chinese medicinal materials are all collected together with the leaves and seeds of Vitex trifolia, Vitex trifolia and Vitex trifolia. They are not a single species of Vitex trifolia.

Product Detail

Product Tags

Essential Information

Alias: apigenin8-c-glucoside

Chemical name: 8- β- D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Molecular formula: c21h20o10 canonical smiles: C1 = CC (= CC = C1C2 = CC (= O) C3 = C (O2) C (= C (C = C3O) o) C4C (C (C (O4) co) o) o) o

Molecular weight: 432.3775

CAS No.: 3681-93-4

Physical And Chemical Properties

Appearance: yellow powder

Source: Craeagus pinnatifida, a Rosaceae plant, has dry and mature fruits.


Therefore, the raw materials of pure Vitex leaves and Vitex seeds are relatively scarce, and the collected Vitex leaves are basically used to distill and refine Vitex oil, which leads the plant extraction manufacturers to abandon the basics and extract Vitexin. Instead, they use hawthorn leaves to extract Vitexin, extract Vitexin from the total flavonoids of Hawthorn Leaves through extraction, separation, purification and other processes, and finally make a freeze-dried preparation.

Vitexin is mainly used to treat cardiovascular diseases. The purity of Vitexin is generally required to be > 98% (HPLC). Vitexin for injection has been used in clinical medicine. The main functions of Vitexin are promoting blood circulation and removing blood stasis, regulating qi and dredging pulse. It is used for chest obstruction caused by blood stasis. Symptoms include chest tightness, suffocation, tingling in the precordial area, palpitation, forgetfulness, dizziness and tinnitus. Coronary heart disease, angina pectoris, hyperlipidemia, insufficient blood supply of cardiac artery and other symptoms.

Cardiovascular and cerebrovascular diseases are the most common diseases in human beings, and have become the largest cause of death in the world. According to WHO estimates, cardiovascular and cerebrovascular diseases cause at least 12 million deaths worldwide every year, and have become the number one enemy of human health. The high incidence and mortality of cardiovascular diseases guide the direction of drug R & D and production. Cardiovascular and cerebrovascular drugs accounted for 4 of the top 10 best-selling drugs in the world in 2005. There are many kinds of Chinese patent medicines for the treatment of cardiovascular diseases, but there are no more than three kinds (Fuzheng Ningxin, aromatic Wentong, promoting blood circulation and removing blood stasis). From the sales situation in the retail market, Vitexin and other drugs for promoting blood circulation and removing blood stasis have a good sales situation. It is one of the drugs with the fastest growth. The market expands rapidly, has great potential, large market capacity and broad competition space.

Vitexin is also a natural drug component for anti-cancer and anti-tumor. Foreign Diaz reported that flavonoids obtained from Vitex negundo, such as Vitexin, showed extensive cytotoxicity to human cancer cells in bioassay; Massateru et al. Found that bauhinin inhibited the growth of human lung cancer cells (PC-12) and human colon cancer cells (HCT116) in MTT test.

Many plant extraction manufacturers are producing Vitexin plant extracts. In addition to Vitexin extract, such as Vitexin extract and hawthorn extract, they are all producing Vitexin as the effective component index, and the products are also sold to customers with Vitexin as the index. The content index of Vitexin in the extracts of Vitex and hawthorn is basically only about 5%.

I believe you have also seen similar reports on anti-cancer and anti-cancer of Hawthorn: recent studies have found that Hawthorn contains a compound called Vitexin, which has the effect of anti-cancer. Nitrosamine and aflatoxin can induce the occurrence or aggravation of digestive tract cancer. Experimental studies show that hawthorn extract can not only block the synthesis of nitrosamine, but also inhibit the carcinogenic effect of aflatoxin. Therefore, people at high risk of gastrointestinal cancer should often eat hawthorn. For patients with cancer, hawthorn and rice can also be used to cook porridge together in case of dyspepsia, which can not only help digestion, but also play an auxiliary role in anti-cancer.

The chemical content of Vitexin in Hawthorn is far less than that of Vitexin, but because few people really know and understand Vitexin to get rich, the anti-cancer and anti-cancer effect of Vitexin has been locked in the mountains!

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