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Iimveliso

imethyl rosmarinate

Inkcazelo emfutshane:

Igama eliqhelekileyo: methyl rosmarinate

Inombolo yeCAS: 99353-00-1

Ubunzima beMolekyuli: 374.341

Ubuninzi: 1.5 ± 0.1 g / cm3

Indawo yokuBilisa: 655.4 ± 55.0 ° C kwi-760 mmHg

Ifomula yemolekyuli: C19H18O8

Indawo yokunyibilika: n / A

I-MSDS: N/A

Indawo edanyazayo: 236.5 ± 25.0 ° C


Iinkcukacha zeMveliso

Iithegi zeMveliso

Ukusetyenziswa kweMethyl Rosmarinate

I-Methyl rosmarinate yinto engakhuphisaniyo ye-tyrosinase inhibitor ekwanti kwi-Rabdosia serra.Ixabiso layo le-IC50 ye-mushroom tyrosinase yi-0.28 mm, kwaye inokuthintela i-glucosidase [1].

Igama likaMethyl Rosmarinate

Igama lesiTshayina: Methyl rosmarinate

Umsebenzi webhayoloji weMethyl Rosmarinate

Inkcazo:

I-Methyl rosmarinate yinto engakhuphisaniyo ye-tyrosinase inhibitor ekwanti kwi-Rabdosia serra.Ixabiso layo le-IC50 le-mushroom tyrosinase yi-0.28 mm, kwaye inokuthintela i-a-glucosidase [1]

Iindidi ezinxulumeneyo: intsimi yophando > > enye

indlela yokubonisa > > i-enzyme ye-metabolic / iprotease

>> tyrosinase

Ithagethi: IC50: 0.28 mM (mushroom tyrosinase), a -glucosidase[1]

Imbekiselo:[1].ULin L, kunye nabanye.Uvavanyo oluthelekisayo lwe-rosmarinic acid, i-methyl rosmarinate kunye ne-pedalitin eyodwa kwi-Rabdosia serra (MAXIM.) I-HARA njenge-inhibitors ye-tyrosinase kunye ne-α-glucosidase.Ukutya Chem.2011 Dec 1;129(3):884-9.

IiPropati zePhysicochemical zeMethyl Rosmarinate

Ubuninzi: 1.5 ± 0.1 g / cm3

Indawo yokuBilisa: 655.4 ± 55.0 ° C kwi-760 mmHg

Ifomula yemolekyuli: c19h18o8

Ubunzima beMolekyuli: 374.341

Indawo edanyazayo: 236.5 ± 25.0 ° C

Ubunzima obuchanekileyo: 374.100159

PSA: 133.52000

IlogP:2.12

Uxinzelelo lomphunga: 0.0 ± 2.0 mmHg ku-25 ° C

Refractive Index: 1.668

Igama lesiNgesi leePropati zeMethyl Rosmarinate

(2R)-3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate

(2R)-3-(3,4-Dihydroxyphenyl)-1-methoxy-1-oxo-2-propanyl (2E)-3-(3,4-dihydroxyphenyl)acrylate

I-Benzenepropanoic acid, α--[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxy-, i-methyl ester, (αR)-

Inkonzo Yongjian

Inkonzo eCwangcisiweyo yeZixhobo zeNgcaciso zeMichiza yezamayeza zesiNtu zamaTshayina
I-Jiangsu Yongjian Pharmaceutical Technology Co., Ltd. ibandakanyeka ikakhulu kuphando olusisiseko lwezinto ezisebenzayo zamayeza esintu amaTshayina ngaphezulu kweminyaka elishumi.Ukuza kuthi ga ngoku, inkampani yenze uphando olunzulu kwiintlobo ezingaphezu kwe-100 zamayeza esintu aqhelekileyo asetyenziswa eTshayina, kwaye yakhupha amawaka eekhemikhali.

Inkampani inabasebenzi abaphezulu be-R & D kunye novavanyo olugqibeleleyo kunye nezixhobo zokuhlalutya kushishino, kwaye ikhonze amakhulu amaziko ophando lwezenzululwazi.Inokukhawuleza kwaye ihlangabezane neemfuno zabathengi

Ukwahlulwa kokungcola kweziyobisi, ukuLungisa kunye neNkonzo yokuQinisekisa uLwakhiwo
Ukungcola kwiziyobisi kuhambelana ngokusondeleyo nomgangatho, ukhuseleko kunye nokuzinza kwamachiza.Ukulungiswa kunye nokuqinisekiswa kwesakhiwo sokungcola kwiziyobisi kunokusinceda siqonde iindlela zokungcola kunye nokubonelela ngesiseko sokuphucula inkqubo yokuvelisa.Ngoko ke, ukulungiswa kunye nokwahlula ukungcola kubaluleke kakhulu kuphando lweziyobisi kunye nophuhliso.

Nangona kunjalo, umxholo wokungcola kwiyeza liphantsi, umthombo ubanzi, kwaye isakhiwo sininzi sifana necandelo eliphambili.Yeyiphi itekhnoloji enokusetyenziswa ukwahlula kunye nokucoca bonke ukungcola kwichiza nganye nganye kwaye ngokukhawuleza?Zeziphi iindlela neendlela ezisetyenziswayo ukuqinisekisa ubume bobu kungcola?Obu bubunzima kunye nomngeni ojongene namacandelo amaninzi oxubo mayeza, ngakumbi amashishini axuba amayeza ezityalo kunye namayeza elungelo elilodwa lomenzi wechina.

Ngokusekwe kwiimfuno ezinjalo, inkampani iye yasungula ukwahlulwa kokungcola kweziyobisi kunye neenkonzo zokucoca.Ukuxhomekeka kwi-resonance yamagnetic yenyukliya, i-spectrometry yobunzima kunye nezinye izixhobo kunye nobuchwepheshe, inkampani inokuchonga ngokukhawuleza ukwakheka kweekhompawundi ezahluliweyo, ukuze ihlangabezane neemfuno zabathengi.

SPF Animal Experiment
Indawo yolwakhiwo yendawo yovavanyo lwezilwanyana yi-1500 square metres, kubandakanywa i-400 square metres yendawo yovavanyo yenqanaba le-SPF kunye ne-100 yeemitha zesikwere selebhu yenqanaba le-P2 yeseli.Ikhokelwe ngoosonzululwazi base China Pharmaceutical University, yenza iqela lobugcisa elingundoqo elinenani lababuyileyo.Ukubonelela ngeemodeli zezilwanyana ezikumgangatho ophezulu, uyilo lokulinga, iiprojekthi zizonke kunye nezinye iinkonzo zophando lwenzululwazi yebhayoloji, ukufundisa kunye nophuhliso lwemizimveliso.

Umda woShishino

1. Ukutyisa izilwanyana ezincinci

2. Imodeli yezifo zezilwanyana

3. Ukunikezelwa kweprojekthi yasekholejini

4. Uvavanyo lwe-Pharmacodynamic kwi-vivo

5. Uvavanyo lwe-Pharmacokinetic

6. Inkonzo yokulinga iseli yethumba

Amandla Ethu

1. Gxininisa kwimifuniselo yokwenyani

2. Qinisekisa ngokungqongqo inkqubo

3. Utyikitye ngokungqongqo isivumelwano semfihlo

4. Ilabhoratri yeyakho ngaphandle kwamakhonkco aphakathi

5. Iqela lobugcisa lobuchwephesha liqinisekisa umgangatho wokulinga

Imekobume yovavanyo ye-SPF, ukondla umntu owabelwe ngokukhethekileyo, ukulandelela ixesha lokwenyani inkqubela yovavanyo


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