ikhasi_ikhanda_bg

Imikhiqizo

I-Esculin;I-Aesculin;I-Esculoside;I-Bicolorin;I-Escosyl

Incazelo emfushane:

Igama elivamile: aesculin

Igama lesiNgisi: esculin

Inombolo ye-CAS: 531-75-9

Isisindo se-Molecular: 358.297

Ukuminyana: 1.7 ± 0.1 g / cm3

Indawo yokubilisa: 697.7 ± 55.0 ° C ku-760 mmHg

I-Molecular Formula: C15H16O9

Indawo yokuncibilika: 203 ° C

I-MSDS: Inguqulo yaseMelika  

I-Flash Point : 262.8 ± 25.0 ° C


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ukusetshenziswa kwe-Esculin

I-Bioflavonoids, i-antioxidant, ikhuthaza okuqukethwe kwe-vitamin C.

Isenzo sika-Esculin

1. Ukulwa nokuvuvukala kanye ne-analgesia: amagundane afakwe ngaphakathi kwe-intraperitoneally nge-10mg / kg.I-Carrageenan eyenziwe, i-dextrose eyenziwe, i-serotonin eyenziwe kanye ne-histamine eyenza "i-arthritis" ibe nemiphumela evimbelayo, futhi amandla okuvimbela ayengama-35,28,20,8% ngokulandelana Kuphinde kubikwe ukuthi kunomphumela ovimbelayo ku-arthritis eyenziwe nge-formaldehyde, kodwa umphumela uwukuthi ibuthakathaka kunaleyo ye-carrageenan ebangelwa isifo samathambo;Ukuvinjelwa kwe-dextran arthritis akubonakali Kungavimbela ukwakheka kwe-granuloma kumagundane (indlela yebhola likakotini), ukusabela kwe-erythema okubangelwa imisebe ye-ultraviolet ngemuva kwezingulube ze-Guinea, kanye nokwanda kwe-capillary permeability okubangelwa i-histamine Inomphumela we-analgesic obuthakathaka. .

2. Umthelela kumthamo womchamo kanye nokuphuma kwe-uric acid: imizila ehlukahlukene yokuphatha ingathuthukisa ukuphuma kwe-uric acid kumagundane nonogwaja, futhi ayinawo umphumela wokukhipha isisu kumagundane avamile, kodwa ibe nomthelela omkhulu wokukhipha isisu kumagundane.

3.Okunye: i-antibacterial, i-anticoagulant kanye ne-inhibiting aldose reductase ku-lens yamagundane.

Igama lika-Esculin

Igama lesiNgisi :esculin

Igama lesiShayina: Heptachlor hemihydrate |heptachlor hemihydrate |6-( β- D-glucopyranoxy) - 7-hydroxy-2h-1-benzofuran-2-one |esho |ihhashi le-chestnut bark glycoside |i-chestnut bark glycoside Umoya wamaqabunga ayisikhombisa Aescin |Qiyela |i-chestnut bark glycoside |esho |6 - (beta-d-glucopyranoxy) - 7-hydroxy-2h-1-benzofuran-2-one

I-Bioactivity ye-Esculin

Incazelo: i-esculin iyi-fluorescent coumarin glucoside, eyingxenye ephumelelayo yegxolo elimpunga.I-Esculin ithuthukisa ukukhubazeka kwengqondo ekuhlolweni kwesifo sikashukela (i-DN) ngokusebenzisa indlela yokusayina ye-MAPK, futhi isebenzisa ukucindezeleka kwe-antioxidant kanye nemiphumela elwa nokuvuvukala.

Izigaba Ezihlobene: inkundla yocwaningo > > umdlavuza

Ithagethi: p38 MAPK

Ireferensi:

[1].U-Knox K, et al.I-Coumarin Glucoside, Esculin, Yembula Izinguquko Ezisheshayo Esivinini Se-Phloem-Zokuthutha Ekuphenduleni Izimpawu Zendawo.I-Physiol yezitshalo.2018 Okthoba;178(2):795-807.

[2].Ingoma Y, et al.I-Esculin ithuthukisa ukukhubazeka kwengqondo ekuhlolweni kwe-nephropathy yesifo sikashukela futhi idala ukucindezelwa kwe-anti-oxidative kanye nemiphumela elwa nokuvuvukala ngendlela ye-MAPK.UMol Med Rep. 2018 May;17(5):7395-7402.

Izakhiwo ze-Physicochemical of Esculin

Ukuminyana: 1.7 ± 0.1 g / cm3

Indawo yokubilisa: 697.7 ± 55.0 ° C ku-760 mmHg

Indawo yokuncibilika: 203 ° C

I-Molecular Formula: c15h16o9

Isisindo se-Molecular: 358.297

I-Flash Point: 262.8 ± 25.0 ° C

Isisindo esinembile: 358.089996

I-PSA: 358.089996

I-LogP:-1.52

Ukubukeka: ukhilimu powder

I-Steam Pressure: 0.0 ± 2.3 mmHg ku-25 ° C

Inkomba ye-Refractive: 1.689

Izimo Zokugcina

1 Gcina endaweni epholile, eyomile futhi enomoya omuhle.Gcina kude nemithombo yokushisa neyokushisa.Vikela elangeni eliqondile.Ukuvalwa kwephakheji.Izogcinwa ngokuhlukana nama-acids namakhemikhali adliwayo, futhi ukugcinwa okuxubile akufanele kuvunyelwe.Indawo yokugcina kufanele ifakwe izinto ezifanele ukuqukatha ukuvuza.

2. I-Argon igcwele isitoreji esivaliwe

Ukuzinza: sebenzisa futhi ugcine ngokuya ngokucaciswa ngaphandle kokubola futhi ugweme ukuthintana nama-oxide

Ukunyibilika kwamanzi: imodeli encibilikayo

Isakhiwo samangqamuzana

1. Inkomba ye-Molar refractive: 77.35

2. Ivolumu ye-Molar (cm3 / mol): 202.6

3. Ivolumu eqondile ye-Isotonic (90.2k): 628.5

4. Ukuqina kobuso (dyne / cm): 92.6

5. I-polarizability (10-24cm3): 30.66

Ulwazi Lokuphepha lwe-Esculin

Ikhodi yengozi (iYurophu): F, C, Xi

Isitatimende Sobungozi (eYurophu): R11

Isitatimende Sokuphepha (Europe): s26-s36 / 37 / 39-s45-s24 / 25

Ikhodi Yezokuthutha yezimpahla eziyingozi: UN 2924 3 / PG 2

I-Wgk Germany: 3

Inombolo ye-RTECS: dj3085000

Ikhodi Yempahla: 2942000000

Esculin Customs

Ikhodi Yempahla:2942000000

Igama lesiNgisi lika-Esculin

I-Crataegin

7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside

I-EINECS 208-517-5

i-vitaminc2

Enallachrome

I-Esculetin 6-β-D-glucoside

I-POLYDROM

I-Bicolorin

I-Esculetin 6-O-glucoside

I-Polychrom

7-Hydroxy-2-oxo-2H-chromen-6-yl-β-D-glucopyranoside

I-BICOLOIN

I-7-Hydroxycoumarin-6-yl β-D-Glucopyranoside Sesquihydrate

Esculin

7-Hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-2H-chromen- 2-okukodwa

6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one

I-Esculetin 6-bD-glucoside

2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy) -7-hydroxy-

I-7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside hydrate (1:1)

I-Aesculin

I-MFCD00006879

I-Esculetin-6-O-glucoside

2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy) -7-hydroxy-, hydrate (1:1)

I-Escosyl


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