China Gold Supplier for Atractylodin - Ophiopogonin D Cas No.945619-74-9 – Yongjian
China Gold Supplier for Atractylodin - Ophiopogonin D Cas No.945619-74-9 – Yongjian Detail:
Ophiopogon Saponin D Name
English Name: (1β,3β,25R)-3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-6-deoxy-β-D-galactopyranoside
Bioactivity of Ophiopogon Japonicus Saponin D
Description: Ophiopogon D is a rare natural C29 steroidal glycoside isolated from the tuber of Ophiopogon japonicus. Ophiopogonin D is a CYP2J3 inducer that increases CYP2J2 / eets and PPAR in human umbilical vein endothelial cells (HUVECs) α The expression of Ang II significantly inhibited Ang II induced NF- κ B nuclear translocation, I κ B α Down regulation, intracellular Ca2 + overload and activation of proinflammatory cytokines. Ophiopogonin D has been used to treat inflammation and cardiovascular diseases for thousands of years.
Relevant Categories
Signaling pathway > > transmembrane transport > > calcium channel
Research field > > cardiovascular disease
Signaling pathway > > cell cycle / DNA damage > > PPAR
Research field > > inflammation / immunity
Target
PPARα
NF-κB
Ca2+
Reference Documents: [1]. Wang L , et al. Homo-aro-cholestane, furostane and spirostane saponins from the tubers of Ophiopogonjaponicus. Phytochemistry. 2017 Apr;136:125-132.
[2]. Huang X, et al. Ophiopogonin D and EETs ameliorate Ang II-induced inflammatory responses via activating PPARα in HUVECs. Biochem Biophys Res Commun. 2017 Aug 19;490(2):123-133.
English Alias of Ophiopogon saponin D
(1β,3β,25R)-3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-6-deoxy-β-D-galactopyranoside β-D-Galactopyranoside, (1β,3β,25R)-3-hydroxyspirost-5-en-1-yl O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[β-D-xylopyranosyl-(1->3)]-6-deoxy-
(2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-5-hydroxy-2-(((4R,5′R,6R,6aR,6bS,8aS,8bR,9S,10R,11aS,12aS,12bS)-4-hydroxy-5′,6a,8a,9-tetramethyl-1,3,3′,4,4′,5,5′,6,6a,6b,6′,7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2′-pyran]-6-yl)oxy)-6-methyl-4-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol
Ophiopogonin D
Deacetylophiopogonin C
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Our aim would be to fulfill our shoppers by offering golden company, very good value and good quality for China Gold Supplier for Atractylodin - Ophiopogonin D Cas No.945619-74-9 – Yongjian , The product will supply to all over the world, such as: Amsterdam, United Arab Emirates, Brasilia, Looking forward, we will keep pace with the times, continuing to create new products. With our strong research team, advanced production facilities, scientific management and top services, we will supply high quality products to our customers worldwide. We sincerely invite you to be our business partners for mutual benefits.
By Caroline from Estonia - 2017.03.28 12:22
A nice supplier in this industry, after a detail and careful discussion, we reached a consensus agreement. Hope that we cooperate smoothly.
By Kelly from Guyana - 2018.10.01 14:14
