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Application Of Neoisoliquiritin

Neoisoliquiritin, separated from spatholobus suberectus, is directly combined with GRP78 for regulation β- Catenin pathway inhibits proliferation and induces apoptosis in breast cancer cells.

Name of Neoisoliquiritin

English Name :Neoisoliquiritin

Bioactivity of Neoisoliquiritin

Description: Neoisoliquiritin is separated from spatholobus suberectus. Neoisoliquiritin is directly combined with GRP78 for regulation β- Catenin pathway inhibits proliferation and induces apoptosis in breast cancer cells
Related categories: signal pathway > > apoptosis > > apoptosis
Research field > > cancer
reference: [1]. TangH,etal. Neoisoliquiritigenin Inhibits Tumor Progression by Targeting GRP78- β-  catenin Signaling in Breast Cancer. Curr Cancer Drug Targets.  2018; 18(4):390-399.

Physicochemical Properties Of Neoisoliquiritin

Density: 1.528
Boiling Point: 743.5 ± 60.0 ° C at 760 mmHg
Melting Point: 230-232 ℃
Molecular Formula: c21h22o9
Flash Point: 263.3 ± 26.4 ° C
Exact mass: 418.126373
LogP:0.76
Steam Pressure: 0.0 ± 2.6 mmHg at 25 ° C
Refractive Index: 1.707 

English alias of Neoisoliquiritin

2Y348H1V4W

2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]-, (2E)-

Isoliquiritin

MFCD00272145

2-Propen-1-one,1-(2,4-dihydroxyphenyl)-3-(4-(β-D-glucopyranosyloxy)phenyl)-, (2E)-

4-[(1E)-3-(2,4-Dihydroxyphenyl)-3-oxo-1-propen-1-yl]phenyl β-D-glucopyranoside

Jiangsu Yongjian Pharmaceutical Technology Co., Ltd
Jiangsu Yongjian Pharmaceutical Technology Co., Ltd., established in March 2012, is a high-tech enterprise integrating R & D, production and sales. It is mainly engaged in the production, customization and production process development of active components of natural products, traditional Chinese medicine reference materials and drug impurities. The company is located in China Pharmaceutical City, Taizhou City, Jiangsu Province, including a 5000 square meter production base and a 2000 square meter R & D base. It mainly serves major scientific research institutes, universities and decoction piece production enterprises across the country.
So far, we have developed more than 1500 kinds of natural compound reagents, and compared and calibrated more than 300 kinds of reference materials, which can fully meet the daily inspection needs of major scientific research institutes, university laboratories and decoction pieces production enterprises.
Based on the principle of good faith, the company hopes to sincerely cooperate with our customers. Our aim is to serve the modernization of traditional Chinese medicine.
Advantageous Business Scope Of The Company:
1. R & D, production and sales of chemical reference materials of traditional Chinese medicine;
2. Customized traditional Chinese medicine monomer compounds according to customer characteristics
3. Research on quality standard and process development of traditional Chinese medicine (plant) extract
4. Technology cooperation, transfer and new drug research and development.