Benzoylpaeoniflorin
Tilmaamaha Alaabta
CaadiyanMagaca: benzoyl paeoniflorin
Lambarka CAS:38642-49-8
Magaca Ingiriisiga:benzoylpaeoniflorin
Miisaanka Molecular:584.568
Cufnaanta:1.6 ± 0.1 g / cm3 barta karkarinta: 742.9 ± 60.0 ° C at 760 mmHg
Qaaciidada molecular:c30h32o12 barta dhalaalka: n / A
MSDS: n / a flash point: 243.1 ± 26.4 ° C
Waxqabadka Nafleyda ee Benzoyl paeoniflorin
Sharaxaad:benzoylpaeoniflorin waa iskudhis dabiici ah, kaas oo lagu soo warramey in lagu daweeyo cudurrada wadnaha iyada oo la yareeyo apoptosis.
Qaybaha la xidhiidha:jidka signal > > kale > > kale
Alaabta Dabiiciga ah >> terpenoids iyo glycosides
Goobta cilmi-baarista > > Cudurrada wadnaha iyo xididdada
Tixraac:[1]Xinfeng Zhao, iyo al.Go'aaminta tirada iyo tayada Liuwei Dihuang Kiniiniyada ee HPLC-UV-MS-MS.Joornaalka Sayniska Chromatographic, Vol.45, Sebtembar 2007, 549-552
[2].ZHANG Er-li, iyo al.Saamaynta Benzoylpaeoniflorin ee apoptosis ee Jiirka ee qaba Cudurada Wadnaha.Joornaalka Shiinaha ee Baadhista Shaybaarka, 2011-04.
Astaamaha physicochemical ee benzoyl paeoniflorin
Cufnaanta:1.6 ± 0.1 g / cm3
Barta Karkari:742.9 ± 60.0 ° C at 760 mmHg
Qaanuunka molecular:C30H32O12
Miisaanka Molecular:584.568
Barta Tooshka ah:243.1 ± 26.4 °
Mass sax ah:584.189392
PSA:170.44000 LogP:5.55
Cadaadiska uumiga:0.0 ± 2.6 mmHg at 25 ° C
Tusmada Dib-u-celinta:1.682
Magaca Ingiriisiga ee Benzoylpaeoniflorin
{(3S,5R,6S)-1-({[(4,5-Dihydroxy-2-cyclohexen-1-yl)carbonyl]oxy}methyl)-3-[(1aR)-1H-3,4-dioxacyclobuta [cd] pentalen-1a (2H)-yloxy] -5,6-dihydroxy-4-methyl-2-oxabicyclo[2.2.1] hept-3-yl}methyl benzoate
2-Cyclohexene-1-carboxylic acid, 4,5-dihydroxy-, [(3S,5R,6S)-3-[(benzoyloxy) methyl]-3-[(1aR) -1H-3,4-dioxacyclobuta[cd ] pentalen-1a (2H)-yloxy] -5,6-dihydroxy-4-methyl-2-oxabicyclo[2.2.1] hept-1-yl] methyl ester
β-D-Glucopyranoside, (1aR,2S,3aR,5R,5aR,5bS) -5b-[(benzoyloxy) methyl] tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4- dioxacyclobuta[cd] pentalen-1a(2H)-yl, 6-benzoate
{(1R,2S,3R,5R,6R,8S)-3-[(6-O-Benzoyl-β-D-glucopyranosyl) oxy]-6-hydroxy-8-methyl-9,10-dioxatetracyclo[4.3. 1.0.0] dec-2-yl}methyl benzoate
Jiangsu Yongjian Pharmaceutical Technology Co., Ltd
Jiangsu Yongjian Pharmaceutical Technology Co., Ltd., oo la aasaasay bishii Maarso 2012, waa shirkad farsamo sare ah oo isku dhafan R & D, wax soo saarka iyo iibinta.Waxay inta badan ku hawlan tahay wax soo saarka, habaynta iyo horumarinta habka wax soo saarka ee qaybaha firfircoon ee alaabta dabiiciga ah, alaabta tixraaca daawada dhaqameed ee Shiinaha iyo wasakhda daroogada.Shirkaddu waxay ku taal Shiinaha Pharmaceutical City, Taizhou City, Gobolka Jiangsu, oo ay ku jiraan 5000 mitir oo laba jibbaaran saldhigga wax soo saarka iyo 2000 mitir oo laba jibbaaran R & D.Waxay inta badan u adeegtaa machadyada cilmi-baarista sayniska ee waaweyn, jaamacadaha iyo shirkadaha wax soo saarka goos gooska ee dalka oo dhan.
Ilaa hadda, waxaan soo saarnay in ka badan 1500 nooc oo reagents xarunta dabiiciga ah, iyo barbar dhig iyo calibrated in ka badan 300 nooc oo qalabka tixraaca, kaas oo si buuxda u buuxin kara baahida kormeerka maalinlaha ah ee machadyada cilmi sayniska waaweyn, shaybaarada jaamacadda iyo qaybaha decoction shirkadaha wax soo saarka.
Iyada oo ku saleysan mabda'a niyad-wanaagga, shirkaddu waxay rajaynaysaa inay si daacad ah ula shaqeyso macaamiisheena.Hadafkayagu waa in aan u adeegno casriyaynta dawo dhaqameedka Shiinaha.
Baaxadda ganacsiga faa'iidada leh ee shirkadda
1.R & D iyo iibinta daawada dhaqameed ee Shiinaha iyo alaabta xakamaynta kiimikada;
2.Customized daawada dhaqameed Chinese monomer xeryahooda sida ay sifooyinka macaamiisha
3.Cilmi-baadhis ku saabsan heerka tayada iyo horumarinta habka ee dawo-dhaqameedka Shiinaha (dhirta).
4. Iskaashiga tignoolajiyada, wareejinta iyo cilmi baarista iyo horumarinta daroogada cusub.
Adeegga gaarka ah ee agabka tixraaca kiimikada ee Daawo dhaqameed Shiinees ah
Jiangsu Yongjian Pharmaceutical Technology Co., Ltd. ayaa inta badan ku hawlan cilmi-baarista aasaasiga ah ee walxaha firfircoon ee daawada dhaqameed ee Shiinaha in ka badan toban sano.Ilaa hadda, shirkaddu waxay cilmi-baadhis qoto-dheer ku samaysay in ka badan 100 nooc oo ah dawo-dhaqameedka Shiinaha ee inta badan la isticmaalo, waxaanay soo saartay kumannaan qaybood oo kiimiko ah.
Shirkaddu waxay leedahay shaqaale sare oo R & D ah iyo qalab tijaabo iyo falanqayn sax ah oo ku jira warshadaha, waxayna u adeegtay boqolaal machadyo cilmi baaris cilmiyeed.Waxay si dhakhso ah oo hufan u dabooli kartaa baahida macaamiisha.
Kala-saar Xumo-xumada Daroogada, Diyaarinta iyo Adeegga Xaqiijinta Qaab-dhismeedka
Wasakhda daroogooyinka waxay si dhow ula xiriiraan tayada, badbaadada iyo xasiloonida daroogada.Xaqiijinta diyaarinta iyo qaab dhismeedka wasakhda daroogooyinka waxay naga caawin kartaa inaan fahamno hababka wasakhda iyo bixinta aasaaska hagaajinta habka wax soo saarka.Sidaa darteed, diyaarinta iyo kala-soocidda wasakhdu waxay muhiimad weyn u leedahay cilmi-baarista iyo horumarinta daroogada.
Si kastaba ha ahaatee, waxa ku jira wasakhda daawadu way yar tahay, isha waa ballaadhan tahay, qaab-dhismeedkuna inta badan wuxuu la mid yahay qaybta ugu muhiimsan.Tignoolajiyada noocee ah ayaa loo isticmaali karaa in lagu kala saaro oo lagu nadiifiyo dhammaan wasakhda daawada mid mid iyo si degdeg ah?Waa maxay farsamooyinka iyo hababka loo isticmaalo si loo xaqiijiyo dhismaha wasakhdaas?Tani waa dhibka iyo caqabada ay la kulmaan qaybo badan oo dawooyin ah, gaar ahaan shirkadaha dawooyinka ee dawooyinka dhirta iyo daawaynta patent-ka Shiinaha.
Iyada oo ku saleysan baahiyaha noocaas ah, shirkaddu waxay bilawday adeegyada kala soocida wasakhda iyo nadiifinta daroogada.Ku tiirsanaanta nukliyeerka magnetic nukliyeerka, spectrometry mass iyo qalabka kale iyo teknoolajiyada, shirkaddu waxay si dhakhso ah u aqoonsan kartaa qaab-dhismeedka xeryahooda kala go'ay, si loo daboolo baahiyaha macaamiisha.
Tijaabada Xayawaanka ee SPF
Bedka dhismaha ee goobta tijaabada xayawaanku waa 1500 mitir oo laba jibbaaran, oo ay ku jiraan 400 mitir oo laba jibbaaran oo aag tijaabo ah oo heerka SPF ah iyo 100 mitir oo laba jibbaaran oo ah shaybaadhka unugyada heerka P2.Oo ay hogaaminayaan saynisyahano ka tirsan Jaamacadda Pharmaceutical ee Shiinaha, waxay samaysaa koox farsamo oo xudun u ah tiro dad ah oo soo noqday.Bixi noocyo xayawaan oo tayo sare leh, naqshadeynta tijaabada, mashaariicda guud iyo adeegyada kale ee cilmi-baarista cilmiga noolaha, barida iyo horumarinta warshadaha.
Baaxadda Ganacsiga:
1. quudinta xoolaha yar
2. Qaabaynta cudurada xoolaha
3. Dib-u-soo-saarka mashruuca kulliyadda
4. Qiimaynta Pharmacodynamic in vivo
5. Qiimaynta farmashiyaha
6. Adeegga tijaabada unugyada burada
Awoodeena:
1. Diirada saar tijaabooyinka dhabta ah
2. Si adag u habeeyaan habka
3. Si adag u saxiix heshiiska sirta
4. Shaybaadh u gaar ah oo aan lahayn xiriiriye dhexdhexaad ah
5. Kooxda farsamada ee xirfadlayaasha ah ayaa dammaanad qaadaya tayada tijaabada ah
Deegaanka tijaabada SPF, quudinta qofka si gaar ah loo xilsaaray, la socodka wakhtiga dhabta ah ee horumarka tijaabada ah
