Neoisoliquiritin, Neoisoliquiritigenin
Tšebeliso ea Neoisoliquiritin
Neoisoliquiritin, e arohaneng le spatholobus suberectus, e kopantsoe ka ho toba le GRP78 bakeng sa taolo ea β- Catenin tsela e thibela ho ata le ho etsa hore apoptosis e be lisele tsa kankere ea matsoele.
Lebitso la Neoisoliquiritin
Lebitso la Senyesemane: Neoisoliquiritin
Bioactivity ea Neoisoliquiritin
Tlhaloso: Neoisoliquiritin e arotsoe ho spatholobus suberectus.Neoisoliquiritin e kopantsoe ka kotloloho le GRP78 bakeng sa taolo ea β- Catenin tsela e thibelang ho ata le ho etsa hore apoptosis e be liseleng tsa mofetše oa matsoele.
Likarolo tse amanang: tsela ea matšoao > > apoptosis > > apoptosis
Sebaka sa lipatlisiso> > kankere
tšupiso: [1].TangH, etal.Neoisoliquiritigenin E Thibela Tsoelo-pele ea Hlahala ka ho Lebela GRP78- β-catenin Letšoao la Kankere ea Matsoele.Lipheo tsa Lithethefatsi tsa Kankere ea Curr.2018;18(4):390-399.
Lintho tsa Physicochemical tsa Neoisoliquiritin
Boima: 1.528
Ntho e Belang: 743.5 ± 60.0 ° C ho 760 mmHg
Sebaka se qhibilihang: 230-232 ℃
Foromo ea molek'hule: c21h22o9
Flash Point: 263.3 ± 26.4 ° C
Boima bo nepahetseng: 418.126373
Lethathamo: 0.76
Khatello ea Mouoane: 0.0 ± 2.6 mmHg ho 25 ° C
Index ea Refractive: 1.707
Lebitso la Senyesemane la Neoisoliquiritin
2Y348H1V4W
2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]-, (2E)-
Isoliquiritin
MFCD00272145
2-Propen-1-one,1-(2,4-dihydroxyphenyl)-3-(4-(β-D-glucopyranosyloxy)phenyl)-, (2E)-
4-[(1E)-3-(2,4-Dihydroxyphenyl)-3-oxo-1-propen-1-yl]phenyl β-D-glucopyranoside
Jiangsu Yongjian Pharmaceutical Technology Co., Ltd
Jiangsu Yongjian Pharmaceutical Technology Co., Ltd., e thehiloeng ka Hlakubele 2012, ke khoebo ea theknoloji e phahameng e kopanyang R & D, tlhahiso le thekiso.Haholo-holo e kopanela tlhahisong, ho itloaetsa le nts'etsopele ea ts'ebetso ea tlhahiso ea likarolo tse sebetsang tsa lihlahisoa tsa tlhaho, lisebelisoa tsa setso tsa meriana ea Chaena le litšila tsa lithethefatsi.Khamphani e sebakeng sa China Pharmaceutical City, Taizhou City, Profinseng ea Jiangsu, ho kenyeletsoa setsi sa tlhahiso ea lisekoere-mithara tse 5000 le setsi sa R&D sa 2000 metres.E sebeletsa haholo litsi tse kholo tsa lipatlisiso tsa mahlale, liunivesithi le likhoebo tsa tlhahiso ea likotoana tsa li-decoction naheng ka bophara.
Ho fihlela joale, re ntlafalitse mefuta e fetang 1500 ea li-reagents tsa tlhaho tsa tlhaho, 'me re bapisa le ho lekanya mefuta e fetang 300 ea lisebelisoa tsa litšupiso, tse ka kopanang ka botlalo le litlhoko tsa tlhahlobo ea letsatsi le letsatsi tsa litsi tse kholo tsa lipatlisiso tsa mahlale, lilaboratori tsa univesithi le likhoebo tsa tlhahiso ea decoction.
E itšetlehile ka molao-motheo oa tumelo e ntle, k'hamphani e tšepa ho sebelisana le bareki ba rona ka tieo.Sepheo sa rona ke ho sebeletsa ntlafatso ea meriana ea setso ea Chaena.
Melemo ea Khoebo ea Khampani:
1. R & D, tlhahiso le thekiso ea lisebelisoa tsa litšupiso tsa lik'hemik'hale tsa meriana ea setso ea Chaena;
2. Metsoako e ikhethileng ea meriana ea setso ea China monomer ho latela litšobotsi tsa bareki
3. Patlisiso ka maemo a boleng le nts'etsopele ea ts'ebetso ea moriana oa setso oa Machaena (semela).
4. Tšebelisano ea thekenoloji, phetisetso le lipatlisiso le nts'etsopele ea lithethefatsi tse ncha.
