Orientin
Faʻaaogaina o Orientin
O le Orientin o se flavonoids fa'anatura fa'ale-natura fa'atasi ma uiga fa'aola eseese, e aofia ai le fa'ama'i, fa'ama'i, fa'ama'i, fa'ama'i, puipuiga o le fatu ma isi.O le Orientin o se sui o le neuroprotective, lea e talafeagai mo togafitiga o tiga o le neuropathic.
Bioactivity o Orientin
Fa'amatalaga:orientin o se flavonoids fa'anatura fa'aolaola fa'atasi ma le tele o uiga fa'aola, e aofia ai le anti-inflammatory, antioxidant, anti-tumour, puipuiga o le fatu ma isi.O le Orientin o se sui o le neuroprotective, lea e talafeagai mo togafitiga o tiga o le neuropathic.
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Rfa'amatalaga:[1].Dhakal H, et al.A'afiaga fa'alavelave ole orientin ile mast cell-mediated allergic inflammation.Pharmacol Rep. 2020 Ian 24.
[2].Guo D, et al.Orientin ma tiga o le neuropathic i isumu faʻatasi ma le faʻaogaina o neura.61Int Immunopharmacol.2018 Me;58:72-79.
Meatotino Physicochemical o Orientin
Malosi: 1.8 ± 0.1 g / cm3
Fa'apuna: 816.1 ± 65.0 ° C ile 760 mmHg
Lisi Lisi: 260-285 º C
Fuafuaga mole: C21H20O11
Malosi mole: 448.377
Fa'asao: 289.1 ± 27.8 ° C
Misasa'o: 448.100555
PSA: 201.28000
LogP: 1.58
Fa'aaliga: pa'u samasama
Ausa Malosi: 0.0 ± 3.1 mmHg i le 25 ° C
Fa'asino Upu: 1.767
Suavai Suavai: 1 M
NaOH: soluble1mg/ml, manino, moli samasama
Fa'amatalaga saogalemu Digitalis
Fa'amatalaga Saogalemu (Europa): 24/25
La'u felauaiga o oloa mata'utia: nonh mo ituaiga uma o felauaigaRTECS号:DJ3009300
Toe iloilo tusitusiga a Orientin
Eseesega o le C-glycosylflavone isomer pairs orientin/isoorientin ma vitexin/isovitexin fa'aaoga HPLC-MS fua sa'o le mamafa ma i-puna CID.
Phytochem.Anal.16(5), 295-301, (2005)
O le HPLC-MS o loʻo faʻaaogaina le faʻalavelave faʻalavelave faʻafuaseʻi (CID) ua faʻaaogaina mo le faʻamaoniaina o le C-glycosylflavone isomer pairs orientin / isoorientin ma vitexin / isovitexin.HPLC-CID/MS su'esu'ega oloa..
O aʻafiaga faʻamalosi ma le cardioprotective o le fua Lagenaria siceraria i NG-nitro-L-arginine methyl ester (L-NAME) faʻaosoina isumu toto maualuga.
Pharm.Paiola.50(11), 1428-35, (2012)
Lagenaria siceraria (Molina) Standl.(Cucurbitacae) (LS) ua lipotia mai e iai le cardioprotective, antihyperlipidemic, ma le diuretic activities.To iloilo antihypertensive ma cardioprotective ef...
Atinaʻe ma le faʻamaoniaina o se auala HPTLC mo le faʻatusatusa tutusa o le isoorientin, isovitexin, orientin, ma le vitexin i flavonoids laʻau bamboo.
J. AOAC Int.93(5), 1376-83, (2010)
O se auala faigofie HPTLC ua atiaʻe mo le fuafuaina faʻatasi o le isoorientin, isovitexin, orientin, ma vitexin, mama uma ma faʻataʻitaʻiga faʻapisinisi o flavonoids lau-laʻau bamboo.O le flavon...
Fa'aigoa fa'aPeretania o Orientin
(1S)-1,5-Anhydro-1-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-8-yl]-D-glucitol
2-(3,4-Dihydroxyphényl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran- 2-yl]-4H-chromén-4-tasi
Orientin 8-C-β-D-glucopyranoside
3',4',5,7-tetrahydroxyflavone-8-C-glucoside
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R) -3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran- 2-yl]-4H-chromen-4-i luga
Luteolin-8-C-glucoside
3',4',5,7-tetrahydroxyflavone 8-glucoside
4H-1-Benzopyran-4-tasi, 2-(3,4-dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-
D-Glucitol, 1,5-anhydro-1-C-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-8-yl]-, (1S) -
Orientin
lutexin
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R) -3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran- 2-yl]-4H-chromen-4-tasi
2-(3,4-Dihydroxyphenyl)-8-bD-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
