Orientin
Kev siv Orientin
Orientin yog ib txwm tshwm sim bioactive flavonoid nrog ntau yam kev lom neeg yam ntxwv, nrog rau kev tiv thaiv kab mob, antioxidant, tiv thaiv qog, tiv thaiv lub plawv thiab lwm yam.Orientin yog ib qho kev cog lus neuroprotective tus neeg sawv cev, uas yog tsim rau kev kho mob ntawm neuropathic mob.
Bioactivity ntawm Orientin
Nqe lus piav qhia:Orientin yog ib txwm tshwm sim bioactive flavonoid nrog ntau yam kev lom neeg, nrog rau kev tiv thaiv kab mob, antioxidant, tiv thaiv qog, tiv thaiv lub plawv thiab lwm yam.Orientin yog ib qho kev cog lus neuroprotective tus neeg sawv cev, uas yog tsim rau kev kho mob ntawm neuropathic mob.
Pawg muaj feem:kev tshawb fawb teb > > mob cancer
Teeb liab txoj kev > > lwm yam > > lwm yam
Kev tshawb fawb teb > > kab mob neurological
Rkev siv:[1].Dhakal H, et al.Inhibitory teebmeem ntawm orientin nyob rau hauv mast cell-mediated allergic o.Pharmacol Rep. 2020 Lub ib hlis ntuj 24.
[2].Guo D, et al.Orientin thiab neuropathic mob nyob rau hauv nas nrog tus txha caj qaum ligation.61 Int Immunopharmacol.Lub Tsib Hlis 2018; 58: 72-79.
Physicochemical Properties ntawm Orientin
Qhov ceev: 1.8 ± 0.1 g / cm3
Boiling Point: 816.1 ± 65.0 ° C ntawm 760 mmHg
Melting Point: 260-285 ºC
Cov roj formula: C21H20O11
Molecular Luj: 448.377
Flash Point: 289.1 ± 27.8 ° C
Qhov tseeb Mass: 448.100555
PSA: 201.2800
PIB: 1.58
Cov tsos: daj hmoov
Vapor Siab: 0.0 ± 3.1 mmHg ntawm 25 ° C
Refractive Index: 1.767
Dej Solubility: 1 M
NaOH: soluble1mg / ml, ntshiab, daj txiv kab ntxwv
Digitalis cov ntaub ntawv kev nyab xeeb
Nqe lus hais txog kev nyab xeeb (Tebchaws Europe): 24 / 25
Kev thauj mus los ntawm cov khoom txaus ntshai: nonh rau txhua hom kev thaujRTECS 号: DJ3009300
Kev tshuaj xyuas cov ntaub ntawv ntawm Orientin
Distinction ntawm C-glycosylflavone isomer khub orientin/isoorientin thiab vitexin/isovitexin siv HPLC-MS pes tsawg qhov ntsuas thiab hauv-qhov CID.
Phytochem.Qhov ntswg.16(5), 295-301, (2005)
HPLC-MS siv kev sib tsoo induced dissociation (CID) tau siv rau kev txheeb xyuas ntawm C-glycosylflavone isomer khub orientin/isoorientin thiab vitexin/isovitexin.HPLC-CID/MS analyses prod..
Antihypertensive thiab cardioprotective teebmeem ntawm Lagenaria siceraria txiv hmab txiv ntoo hauv NG-nitro-L-arginine methyl ester (L-NAME) induced hypertensive nas.
Pharm.Biol.50(11), 1428-35, (2012)
Lagenaria siceraria (Molina) Standl.(Cucurbitacae) (LS) tau tshaj tawm tias muaj cardioprotective, antihyperlipidemic, thiab diuretic kev ua ub no.To soj ntsuam antihypertensive thiab cardioprotective ef ...
Kev txhim kho thiab siv tau ntawm HPTLC txoj kev rau tib lub sijhawm kom muaj nuj nqis ntawm isoorientin, isovitexin, orientin, thiab vitexin hauv xyoob-nplooj flavonoids.
J. AOAC Int.93(5), 1376-83, (2010)
Ib txoj hauv kev yooj yim HPTLC tau tsim los rau kev txiav txim siab ib txhij ntawm isoorientin, isovitexin, orientin, thiab vitexin, ob qho tib si ntshiab thiab hauv cov qauv lag luam ntawm xyoob-nplooj flavonoids.Cov flavon ...
English Alias ntawm Orientin
(1S)-1,5-Anhydro-1-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-8-yl]-D-glucitol
2-(3,4-Dihydroxyphényl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran- 2-yl]-4H-chromén-4-ib
Orientin 8-C-β-D-glucopyranoside
3',4',5,7-tetrahydroxyflavone-8-C-glucoside
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran- 2-yl]-4H-chromen-4-on
Luteolin-8-C-glucoside
3', 4', 5,7-tetrahydroxyflavone 8-glucoside
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-
D-Glucitol, 1,5-anhydro-1-C-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-8-yl]-, (1S) -
Orientin
lutexin ua
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran- 2-yl]-4H-chromen-4-ib
2-(3,4-Dihydroxyphenyl)-8-bD-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-ib
