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Imikhiqizo

I-Platycodin D CAS No. 58479-68-8

Incazelo emfushane:

I-Platycodon grandiflorum saponin D iyinhlanganisela ye-crystalline powder emhlophe enefomula yamakhemikhali C57H92O28.

Igama langaphandle:i-platycodin D

I-Chemical Formula:I-C57H92O28 Isisindo se-Molecular: 1224.38

Inombolo ye-CAS:58479-68-8 Isicelo: ukuzimisela okuqukethwe


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ulwazi Olubalulekile

Umthombo wokukhipha:I-Platycodon grandiflorum (Jacq.) A.DC.Izimpande ezomile.

Imodi yokutholwa:I-HPLC ≥ 98%.

Imininingwane:20mg, 50mg, 100mg, 500mg, 1g (ingapakishwa ngokwezidingo zekhasimende).

Umlingiswa:Kuyimpushana emhlophe ecwebezelayo.

Inhloso:Isetshenziselwa ukunquma okuqukethwe.

Ukulahlekelwa ekumisweni:≤ 2%

Ubumsulwa:95%, 98%, 99%

Indlela yokuhlaziya:I-HPLC-DAD ^ noma / kanye^ HPLC-ELSD

Izindlela zokuhlonza:i-mass spectrometry (isisindo), i-nuclear magnetic resonance (NMR)

Isitoreji:ivalwe futhi ivikelwe ekukhanyeni, -20 ℃.

Izinyathelo zokuzivikela:Lo mkhiqizo kufanele ugcinwe ekushiseni okuphansi futhi womile.Imikhiqizo ekhethekile kufanele igcinwe ngaphansi kwe-nitrogen.Uma ingagcinwa isikhathi eside, okuqukethwe kuzoncishiswa.

Ukufaneleka:iminyaka engu-2

Ingakwazi ukuhlangabezana nenani elikhulu lezidingo ezingaphezu kwezinga legram.Sicela uthintane ukuze uthole imininingwane.

I-Bioactivity ye-Platycodin D

Incazelo:i-platycodin D iyinhlanganisela ye-saponin ehlukanisiwe nesiqu esawolintshi, okuyi-AMPK α Inomsebenzi wokulwa nokukhuluphala.

 OkuhlobeneCizigaba:indlela yokusayina > > i-epigenetics > > AMPK

Indlela yesiginali > > PI3K / Akt / mTOR indlela yesiginali > > AMPK

Umkhakha wocwaningo > > izifo ze-metabolic

Ithagethi:I-AMPK α [1]

Izithenjwa:[1] UKim HL, et al.I-Platycodin D, i-activator yenoveli ye-AMP-activated protein kinase, inciphisa ukukhuluphala kumagundane e-db/db ngokulawulwa kwe-adipogenesis kanye ne-thermogenesis.I-Phytomedicine.2019 Jan;52:254-263.

I-Physicochemical Properties ye-Platycodin D

Ukuminyana:1.6 ± 0.1 g / cm3

Ifomula ye-molecular:c57h92o28

Isisindo samangqamuzana:1225.324

Isisindo esiqondile:1224.577515

I-PSA:453.28000

I-LogP:-0.69

Inkomba ye-refractive:1.659


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