Hyperoside; Hypercin Cas No. 482-36-0
Bayanin Magunguna
(sunan samfurin) hypericin
[Sunan Turanci] Hyperoside
[alias] hyperin, quercetin 3-galactoside, quercetin-3-o-galactoside.
[kwayoyin kwayoyin halitta] c21h20o12
[nauyin kwayoyin] 464.3763
[C azaman Lamba] 482-36-0
[chemical classification] flavonoids
[source] Hypericum perforatum L
[Takaddun shaida] > 98%
[Tsafety terminology] 1. Kar a shaka kura.2.Idan akwai haɗari ko rashin jin daɗi, nemi kulawar likita nan da nan (nuna alamar sa idan zai yiwu).
[Tsarin magunguna] Hypericin yana yaduwa.Yana da wani muhimmin samfurin halitta tare da nau'o'in ayyukan ilimin lissafi, irin su anti-inflammatory, antispasmodic, diuretic, tari, rage karfin jini, rage yawan cholesterol, haɓakar furotin, analgesia na gida da na tsakiya, da kuma tasirin kariya akan zuciya da tasoshin kwakwalwa.
[Tsarin jiki da sinadarai] Kristal acicular rawaya mai haske.Matsayin narkewa shine 227 ~ 229 ℃, kuma jujjuyawar gani shine - 83 ° (C = 0.2, pyridine).Yana da sauƙin narkewa a cikin ethanol, methanol, acetone da pyridine kuma yana da ƙarfi a ƙarƙashin yanayin al'ada.Yana amsawa tare da hydrochloric acid magnesium foda don samar da ceri ja, kuma ferric chloride yana amsa kore, α-Naphthol dauki yana da kyau.
[Risk terminology] Yana cutarwa idan an hadiye shi.
Ayyukan Pharmacological
1. Hypericin yana da tasiri mai mahimmanci na analgesic na gida, wanda ya fi morphine rauni, ya fi aspirin karfi, kuma ba shi da dogara.Hypericin wani sabon nau'in ciwon daji ne na gida A lokaci guda.
2. Hypericin yana da tasiri mai kyau na karewa akan ischemia-reperfusion na myocardial, ischemia-reperfusion na cerebral da kuma ciwon kwakwalwa.
3. Hypericin yana da tasirin anti-mai kumburi a fili: bayan dasa ƙwallon ulu, an yi wa berayen allurar intraperitoneally tare da 20mg / kg kowace rana don kwanaki 7, wanda ya hana aiwatar da kumburi sosai.
4. Yana da karfi antitussive sakamako.
5. Assimilation.
6. Ƙarfin hanawa na aldose reductase na iya zama da amfani don hana cataracts na ciwon sukari.
Tasirin kariya akan ischemia na myocardial
Hypericin na iya rage apoptosis kudi na cardiomyocytes lalacewa ta hanyar hypoxia reoxygenation, hana sakin lactate dehydrogenase, inganta ayyukan myocardial superoxide dismutase (SOD) a cikin berayen tare da myocardial ischemia-reperfusion rauni, rage samar da malondialdehyde (MDA), hanawa. karuwa da myocardial phosphokinase (CPK) a cikin jini, da kuma rage samuwar oxygen free radical da nitric oxide free radical, Don haka kamar yadda kare myocardium da kuma rage cardiomyocyte rauni da cardiomyocyte apoptosis lalacewa ta hanyar ischemia-reperfusion.
Tasirin kariya akan ischemia cerebral
Hypericin na iya hana raguwar abun ciki na formazan da kyau a cikin yanki na cerebral bayan hypoxia glucose deprivation reperfusion rauni, yana ƙara adadin ƙwayoyin da ke tsira a cikin cortex da striatum na yanki na cerebral a cikin yankin ischemic, kuma ya sa tsarin halittar neurons ya cika kuma ya rarraba sosai.Hana raguwar ayyukan jijiyoyi da aka haifar ta hanyar raunin raunin da ya faru na rashi glucose hypoxia.Hana raguwar ayyukan SOD, LDH da glutathione peroxidase (GSHPx).Tsarinsa na iya kasancewa yana da alaƙa da ɓarkewar ɓacin rai, hana shigowar Ca2 da samuwar maganin lipid peroxide.
Tasirin kariya akan hanta da mucosa na ciki
Hypericin yana da tasirin kariya a fili akan naman hanta da mucosa na ciki.Tsarinsa yana da alaƙa da tasirin antioxidant, yana haɓaka dawo da matakin N0 zuwa al'ada da haɓaka ayyukan SOD.
Antispasmodic analgesic sakamako
Binciken ya gano cewa an samar da tasirin analgesic na hypericin ta hanyar rage Ca 2 a cikin jijiyoyi masu raɗaɗi.A lokaci guda, hypericin na iya hana ƙwayar Ca 2 da ke haifar da babban potassium, yana nuna cewa hypericin kuma yana toshe tashar Ca a cikin nama na jijiyoyi.An kara ba da shawarar cewa hypericin na iya zama mai toshe tashar Ca 2.Binciken asibiti ya nuna cewa allurar hypericin tana kama da atropine a cikin maganin dysmenorrhea na farko.Sai dai ƴan illolin bacci, ba shi da wani mugun nufi kamar tachycardia, mydriasis da ƙonawa.Yana da manufa antispasmodic da analgesic.
Hypolipidemie sakamako
Hypericin na iya rage yawan maganin TC kuma yana haɓaka rabon HDL / TC a cikin ƙananan berayen masu kitse, yana nuna cewa hypericin na iya rage cholesterol, daidaita lipid na jini, da haɓaka ayyukan HDL da SOD a cikin mice.Wannan tasirin zai iya rage yawan lalacewar superoxide free radical zuwa endothelium na jijiyoyin jini a cikin hyperlipidemia, kuma yana da tasiri ga bazuwar da kuma metabolism na lipid peroxide don kare endothelium na jijiyoyin jini.
Haɓaka aikin rigakafi
Hypericin a allurai na 300 mg / kg da 150 mg / kg a cikin vivo na iya hana ma'aunin thymus, haɓakar ƙwayoyin lymphocytes T da B, da phagocytosis na macrophages peritoneal;A 59 MG / kg, yana haɓaka haɓaka t da b hymphocytes da pavhocytosis na lalata lalata Macrophages.Hypericin a kashi na 50 ~ 6.25 ml a cikin vitro zai iya inganta haɓakar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar kuma ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar kuma za ta iya inganta karfin T-lymphocytes don samar da IL-2;Hypericin a 6.25 g / ml yana haɓaka ikon macrophages peritoneal linzamin kwamfuta zuwa phagocytize neutrophils, kama daga 12.5 zuwa 3.12 μG / ml yana haɓaka ikon macrophages peritoneal na linzamin kwamfuta don sakin No.
Antidepressant sakamako
Hypothalamic pituitary adrenal (HPA) kunnawa shine canjin ilimin halitta na yau da kullun a cikin marasa lafiya da matsanancin baƙin ciki, wanda ke da alaƙa da wuce kima na haɓakar adrenocorticotropic hormone (ACTH) da cortisol.Hypericin na iya daidaita aikin axis na HPA kuma ya rage matakan ACTH da corticosterone, don yin rawar antidepressant.
Gama Magani
Ciwujia capsule
Acanthopanax senticosus capsule shiri ne tare da Acanthopanax senticosus kara da tsantsa ganye azaman ɗanyen abu.Babban bangaren shine flavonoids, wanda hypericin shine babban bangaren aiki na ganyen Acanthopanax senticosus.
Babban alamun: inganta yanayin jini da kuma cire tsangwama na jini.Ana amfani da shi don ciwon ƙirji da cututtukan zuciya wanda ya haifar da tsawan jini.Alamomin sun hada da ciwon kirji, daurewar kirji, bugun zuciya, hauhawar jini, da dai sauransu. na da nakasu ga kasawar saifa da koda da jini da Yin.
Xinan capsule
Shiri ne da aka yi da ganyen hawthorn, wanda ke da wadatar flavonoids, wanda hypericin yana daya daga cikin manyan abubuwan.
Babban alamun: faɗaɗa tsarin jijiyoyin jini na jijiyoyin jini, inganta wadatar jini na myocardial da rage lipid na jini.Ana amfani da ita wajen magance cututtukan zuciya, angina pectoris, datse kirji, bugun zuciya, hauhawar jini, da sauransu.
Qiyue Jiangzhi kwamfutar hannu
Qiyue Jiangzhi kwamfutar hannu wani tsantsar maganin gargajiyar kasar Sin ne mai rage lipid da aka shirya ta hanyar fitar da ingantattun sassan magungunan gargajiya na kasar Sin kamar su hawthorn (wanda aka hade) da Astragalus membranaceus.Ɗaya daga cikin mahimman abubuwan da ake amfani da su na hawthorn shine flavonoids, wanda abun ciki na hypericin yana da yawa.
Babban alamomi: rage lipid na jini da kuma laushi tasoshin jini.Ana amfani da shi don haɓaka zagawar jini na jijiyoyin jini da yaƙi da arrhythmia da hyperlipidemia.
Xinxuening kwamfutar hannu
Kwamfutar Xinxuening shiri ne da aka yi da magungunan gargajiya na kasar Sin irin su hawthorn da pueraria.Hawthorn ita ce maganin jam'iyyar mu.Ya ƙunshi ursolic acid, Vitexin rhamnoside, hypericin, citric acid, da dai sauransu, wanda hypericin shine babban bangaren.
Babban alamun: haɓaka zagayawa na jini da cire tsangwama na jini, zubar da lamurra da kuma kawar da ciwo.Ana amfani da shi don ciwon ƙirji na ƙirji da vertigo wanda ke haifar da stasis na jini na zuciya da haɗin gwiwar kwakwalwa, da cututtukan zuciya na zuciya, hauhawar jini, angina pectoris da hyperlipidemia.
Yukexin capsule
Yukexin capsule shiri ne na likitancin gargajiya na kasar Sin da aka samar daga wani tsohon magani, wanda ya hada da Hypericum perforatum, kernel jujube daji, haushin Albizzia, Gladiolus da sauran magungunan gargajiya na kasar Sin.Ya ƙunshi hypericin, quercetin, quercetin, chlorogenic acid, caffeic acid, yimaning, hypericin da sauran abubuwa.
Babban alamun: damuwa na tunanin mutum wanda ke haifar da rashin natsuwa na hanta qi da mummunan yanayi.
