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Imikhiqizo

I-Astragaloside Ngifake Isithombe
  • Astragaloside I

Astragaloside I

Incazelo emfushane:

Igama Elivamile: astragaloside I

Igama lesiNgisi: astragaloside I

Inombolo ye-CAS: 84680-75-1

Isisindo se-Molecular: 869.04

Ukuminyana: 1.4 ± 0.1 g / cm3

Indawo yokubilisa: 910.6 ± 65.0 ° C ku-760 mmHg

I-Molecular Formula: C45H72O16

Indawo Encibilikayo: N/A

I-MSDS: Inguqulo yesiShayina kanye nenguqulo yaseMelika

I-Flash Point: 265.5 ± 27.8 ° C


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ukusetshenziswa kwe-Astragaloside I

I-Astragaloside I iyinhlanganisela yemvelo ehlukanisiwe ne-Astragalus.

Igama le-Astragaloside I

Igama lesiNgisi: 3-O-β-(2',3'-di-O-acetyl)-D-xylopyranosyl-6-O-β-D-glucopyranosyl-cycloastragenol

I-Bioactivity ye-astragaloside I

Incazelo: i-astragaloside I iyinhlanganisela yemvelo ehlukanisiwe ne-Astragalus

Izigaba Ezihlobene: indlela yesiginali > > okunye > > okunye

Inkambu yocwaningo > > abanye

Imikhiqizo yemvelo > > ama-terpenoids nama-glycosides

Izikhombo: [1] JIN Yi-qun, et al.Ukunqunywa kokuqukethwe kwe-astragaloside-I ku-Qidan Jiannao Granules nge-HPLC-ELSD.I-Acta Chinese Medicine and Pharmacology, 2006-02

[2].Wang chunhong, et al.Ukunquma Okuqukethwe kwe-Astragaloside I ku-Shuxing Oral by Dual Wavelength TLC-Scanning.Usokhemisi waseChina, 2005-05

Izakhiwo zePhysicochemical ze-Astragaloside I

Ukuminyana: 1.4 ± 0.1 g / cm3

Indawo yokubilisa: 910.6 ± 65.0 ° C ku-760 mmHg

I-Molecular Formula: C45H72O16

Isisindo se-Molecular: 869.04

I-Flash Point: 265.5 ± 27.8 ° C

I-PSA: 240.36000

I-LogP:0.94

Ukubukeka: Ikristalu emhlophe

I-Steam Pressure: 0.0 ± 0.6 mmHg ku-25 ° C

Inkomba ye-refractive: 1.603

Ikhodi ye-AstrTransport yezimpahla eziyingozi: i-nonh yazo zonke izindlela ze-transportagaloside I Ulwazi Lokuphepha

Isibizo sesiNgisi se-Astragaloside I

2,5-Bis[1-(1,1-dimethyl-2-propenyl)-1H-indol-3-yl]-3,6-dimethoxy-2,5-cyclohexadiene-1,4-dione

i-asterriquinone dimethyl ether

I-cyclosiversioside B

Astragaloside I

2,5-dimethoxy-3,6-bis[1-(2-methylbut-3-en-2-yl)-1H-indol-3-yl]cyclohexa-2,5-diene-1,4-dione

2,5-bis[1-(1,1-dimethylallyl)-1H-indol-3-yl]-3,6-dimethoxy-1,4-benzoquinone

2,5-bis-[1-(1,1-dimethyl-allyl)-indol-3-yl]-3,6-dimethoxy-[1,4]benzoquinone

I-Asterrichinon-dimethylether

i-asterriquinone A1

β-D-Glucopyranoside,(3β,6α,16β,20R,24S) -3-[(2,3-di-O-acetyl-β-D-xylopyranosyl)oxy] -20,24-epoxy-16,25 -dihydroxy-14-methyl-9,19-cyclocholestan-6-yl

(3β,6α,16β,20R,24S)-3-[(2,3-Di-O-acetyl-β-D-xylopyranosyl)oxy]-16,25-dihydroxy-14-methyl-20,24-epoxy -9,19-cyclocholestan-6-yl β-D-glucopyranoside

Isevisi ye-Yongjian

Isevisi Eyenziwe Ngezifiso Yezikhombo Zezinto Zemithi Yendabuko YamaShayina
I-Jiangsu Yongjian Pharmaceutical Technology Co., Ltd. ibambe iqhaza kakhulu ocwaningweni oluyisisekelo lwezinto ezisebenzayo zemithi yendabuko yamaShayina iminyaka engaphezu kweyishumi.Kuze kube manje, inkampani yenze ucwaningo olunzulu ngezinhlobo ezingaphezu kwe-100 zemithi yendabuko yaseShayina evame ukusetshenziswa, futhi yakhipha izinkulungwane zezingxenye zamakhemikhali.

Inkampani inabasebenzi abaphezulu be-R & D kanye nemishini yokuhlola nokuhlaziya ephelele embonini, futhi isize amakhulu ezikhungo zocwaningo lwesayensi.Ingakwazi ukuhlangabezana nezidingo zamakhasimende ngokushesha nangempumelelo

Ukwehlukaniswa Kokungcola Kwezidakamizwa, Isevisi Yokulungiselela kanye Nesakhiwo Sokuqinisekisa
Ukungcola kwezidakamizwa kuhlobene kakhulu nekhwalithi, ukuphepha kanye nokuzinza kwezidakamizwa.Ukulungiswa nokuqinisekiswa kwesakhiwo sokungcola emithini kungasisiza siqonde izindlela zokungcola futhi kunikeze isisekelo sokuthuthukisa inqubo yokukhiqiza.Ngakho-ke, ukulungiswa nokuhlukaniswa kokungcola kubaluleke kakhulu ocwaningweni nasekuthuthukisweni kwezidakamizwa.

Kodwa-ke, okuqukethwe kokungcola emthini kuphansi, umthombo ubanzi, futhi isakhiwo sifana kakhulu nengxenye eyinhloko.Yibuphi ubuchwepheshe obungasetshenziswa ukuhlukanisa nokuhlanza konke ukungcola emthini ngamunye ngamunye futhi ngokushesha?Yiziphi izindlela nezindlela ezisetshenziswayo ukuze kuqinisekiswe ukwakheka kwalokhu kungcola?Lobu ubunzima kanye nenselelo ebhekene namayunithi amaningi emithi, ikakhulukazi amabhizinisi emithi yezitshalo kanye nemithi yobunikazi yamaShayina.

Ngokusekelwe ezidingweni ezinjalo, inkampani yethule izinsiza zokuhlukanisa ukungcola kwezidakamizwa kanye nezinsizakalo zokuhlanza.Ngokuthembela ku-nuclear magnetic resonance, i-mass spectrometry nezinye izinto zokusebenza nobuchwepheshe, inkampani ingakwazi ukubona ngokushesha ukwakheka kwezinhlanganisela ezihlukanisiwe, ukuze ihlangabezane nezidingo zamakhasimende.

I-SPF Animal Experiment
Indawo yokwakhiwa kwendawo yokuhlolwa kwezilwane ingamamitha-skwele ayi-1500, okuhlanganisa namamitha-skwele angama-400 wendawo yokuhlola yezinga le-SPF kanye namamitha-skwele ayi-100 welebhu yeseli yezinga le-P2.Iholwa ososayensi base-China Pharmaceutical University, yakha ithimba lezobuchwepheshe elibalulekile elinenani labantu ababuyayo.Nikeza amamodeli ezilwane ekhwalithi ephezulu, idizayini yokuhlola, amaphrojekthi aphelele kanye nezinye izinsizakalo zocwaningo lwesayensi ye-biomedical, ukufundisa nokuthuthukiswa kwezimboni.

Ububanzi Bebhizinisi

1. Ukuphakelwa kwezilwane ezincane

2. Ukumodela izifo zezilwane

3. Ukunikezwa kwephrojekthi yasekolishi

4. Ukuhlolwa kwe-Pharmacodynamic ku-vivo

5. Ukuhlolwa kwe-Pharmacokinetic

6. Isevisi yokuhlola iseli yesimila

Amandla Ethu

1. Gxila ekuhloleni kwangempela

2. Qinisekisa ngokuqinile inqubo

3. Sayina ngokuqinile isivumelwano sobumfihlo

4. Ilabhorethri Yakho ngaphandle kwezixhumanisi eziphakathi nendawo

5. Ithimba lochwepheshe bezobuchwepheshe liqinisekisa ikhwalithi yokuhlola

Indawo yokuhlola ye-SPF, ukuphakelwa komuntu okwabelwe ngokukhethekile, inqubekelaphambili yokuhlola yokulandelela ngesikhathi sangempela

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