Dimethylfraxetin ;6,7,8-Trimethoxycoumarin
Nkọwapụta ngwaahịa
Aha nkịtị:ash osisi mmewere
Nọmba CAS:6035-49-0
Njupụta:1.2 ± 0.1 g / cm3
Ụdị molekụla:C12H12O5
MSDS:N/A
Aha Bekee:dimethylfraxetin
Ibu Molecular:236.221
Ebe esi mmiri:408.0 ± 45.0 ° C na 760 mmHg
Ebe mgbaze:104-105 ºC
Ebe mgbari:184.3 ± 28.8 Celsius C
Ọrụ ndu nke dimethylfraxetin
Nkọwa:dimethylfraxetin bụ onye na-egbochi carbonic anhydrase nwere uru Ki nke 0.0097 μM.
Ụdị emetụtara:
ụzọ mgbama > > metabolic enzyme / protease >> carbonic anhydrase
Ogige nyocha > > ọrịa kansa
Ngwaahịa eke > > benzoic acid
Ebumnuche:ki: 0.0097 μ M (carbonic anhydrase) [1]
Ọmụmụ in vitro:na CA I, otu ihe a ma ama bụ dimethylfluoxetine (mkpokọta 17), onye na-eme ihe na-egbochi CA I nanomolar.Nke a trimethoxycoumarin bụ nke kacha arụ ọrụ nke coumarin NP ọ bụla n'etiti CA isozymes isii na ọmụmụ a [1].
Kinase:Tupu ekpebie, onye inhibitor (gụnyere dimethylerythromycin) na ngwọta enzyme bụ nke etinyere ya n'ime ụlọ okpomọkụ maka awa 6 iji kwe ka e guzobe mgbagwoju enzyme inhibitor [1]
Ntụaka:[1] Davis RA, et al.Ngwaahịa sitere n'okike nke na-egbochi anhydrases carbonic mmadụ.Bioorg Med Chem.2013 Maachị 15;21 (6): 1539-43 .
Dimethylfraxetin
Njupụta:1.2 ± 0.1 g / cm3
Ebe esi mmiri:408.0 ± 45.0 ° C na 760 mmHg
Ebe mgbaze:104-105 ºC
Ụdị molekụla:c12h12o5
Ibu Molecular:236.221
Ebe mgbari:184.3 ± 28.8 Celsius C
Mass ziri ezi:236.068466
PSA:57.90000
LogP:1.75
Nrụgide Steam:0.0 ± 1.0 mmHg na 25 Celsius
Ndekọ ntụgharị uche:1.545
Ozi nchekwa Dimethylfraxetin
Nkwupụta ihe egwu (Europe): 22
Nkwupụta nchekwa (Europe):22-45
Koodu kọstọm:293220990
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Ụdị omenala Dimethylfraxetin
Koodu kọstọm:293220990
Nchịkọta ndị China:293220990 Ndị ọzọ lactones VAT ọnụego: 17.0% Ụtụ nkwụghachi ụgwọ: 13.0% Usoro nhazi: ọ dịghị MFN tarifu: 6.5% General tarifu: 20.0%
Ihe nkwupụta:aha ngwaahịa, mejupụtara, ọdịnaya na ebumnuche
Nchịkọta:2932209090. ndị ọzọ lactones.VAT: 17.0%.Ọnụ ego nkwụghachi ụtụ: 13.0%..Tarifụ MFN: 6.5%.Tarifu izugbe: 20.0%
Utu aha Bekee nke Dimethylfraxetin
6,7,8-trimethoxychromen-2-otu
6,7,8-Trimethoxy-2H-chromen-2-otu
2H-1-Benzopyran-2-otu, 6,7,8-trimethoxy-
