Esculin;Aesculin;Prunus persica;Bicolorin;Escosyl
Application Of Esculin
Bioflavonoids, antioxidant, contentum vitaminum C promovere.
Actio Esculin
1. Anti inflammatio et analgesia: mures intraperitonealiter cum 10 mg / kg injectae.Carrageenan adductus, dextroso adductus, serotonin adductus et histamine "arthritis" effectus inhibitores habuit, et intensitates inhibitoriae 35,28,20,8% relativum etiam nuntiaverunt effectum inhibitorium habere in arthritis formaldehyde inducto, sed effectus est. debilior quam carrageenan arthritis inducta;Inhibitio arthritis dextranae non patet Inhibere formationem granulomae in muribus (globi cottonis methodi), erythema reactionem causatum per radiorum ultraviolacum in dorso porcorum Guineae, et augmentum permeabilitatis capillaris ex histamine. Effectum analgesicum infirmum habet .
2. Effectus urinae volubilis et acidi urici excretionis: variae administrationis itinera augere possunt excretionem acidum uricum in muribus et leporibus, et nullam urinam habent in muribus normalibus, sed significantes effectus urinam habent in muribus.
3.Alii: antibacterial, anticoagulans et inhibens aldose reductasi in rat lens.
Nomen Esculin
Nomen anglicus: esculin
Chinese Name:Heptachlorum hemihydratum |heptachlor hemihydratum |6-（ β- D-glucopyranoxy - 7-hydroxy-2h-1-benzofuran-2-one |aescin |equus castanei corticis glycoside |cortex castaneus glycosidis Septem folium spiritus Aescin |Qiyeling |cortex castaneus glycoside |aescin |6 - (beta-d-glucopyranoxyis) - 7-hydroxy-2h-1-benzofuran-2-unum
Bioactivity Esculin
Descriptio: esculinum est glucosidum fluorescens coumarinum, quod est efficax pars cortice cinereo.Esculinum cognitivum detrimentum in diabetica nephropathia experimentali (DN) per MAPK iter significat, et accentus antioxidantos et effectus anti-inflammatorii exercet.
Related Categoriae: campus investigationis > > cancer
Target: p38 MAPK
Relatio:
[1].Knox K, et al.Coumarin Glucoside, Esculin, Reveals Celeri Mutationes in Phloem-Transport Velocitas in Responsione Cues Environmentalis.Plant Physiol.MMXVIII Oct;178(2): 795-807.
[2].Song Y, et al.Esculinum meliorat imminutionem cognitivam in nephropathia diabetica experimentali et inducit accentus anti-oxidativus et effectus anti-inflammatorius per viam MAPK.Mol Med Rep. MMXVIII Maii;17(5): 7395-7402.
Physicochemical Proprietates Esculin
Densitas: 1.7 ± 0.1 g / cm3
Fervens Point: 697.7 ± 55.0 ° C ad 760 mmHg
Punctum punctum: 203 ° C
Formulae hypotheticae: c15h16o9
Pondus hypotheticum: 358.297
Flash Point: 262.8 ± 25.0 ° C
Exige missam: 358.089996
PSA:358.089996
LogP: -1.52
Aspectus: crepito pulveris
Vapor Pressura: 0.0 ± 2.3 mmHg in 25° C
Index refractivus: 1.689
Repono Conditions
1 Repono in horreis frigido, sicco et bene ventilatis.Ab fomite et calore abstinete fontes.Ab directo solis protegat.Involucrum signare.Seorsim ab acidis et chemicis edulis condietur, et mixta reposita non licebit.Tabularium congruis materiis ad ultrices continendas instruantur.
2. Argon implevit signatum repono
Stabilitas: usus et copia secundum determinationes sine compositione et contactum cum oxydis vitantibus
Aqua Solubility: exemplar solutum
M
1. Index refractivus molaris: 77.35
2. Volumen molarium (cm3 / mol): 202.6
3. Isotonic volumen specificum (90.2k): 628.5
4. Superficies tensio (dyne/cm): 92.6
5. Polarizability (10-24cm3): 30.66
Esculin Safety Information
Hazard code (Europe): F, C, XI .
Periculum Statement (Europe): R11
Salus Statement (Europe): s26-s36/37/39-s45-s24/25
Transportus Codex periculosorum bonorum: UN 2924 3 / PG 2
Wgk Germania: 3
RTECS No.: dj3085000
Consuetudines Codicis: 2942000000
Esculin Consuetudines
Consuetudines Codicis:2942000000
Alias of Esculin
Crataegin
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside
EINECS 208-517-5
vitaminc2
Enallachrome
Esculetin 6-β-D-glucoside
POLYDROM
Bicolorin
Esculetin 6-O-glucoside
Polychrom
7-Hydroxy-2-oxo-2H Chromen-6-yl-β-D-glucopyranoside
BICOLOIN
7-Hydroxycoumarin-6-yl β-D-Glucopyranoside Sesquihydratorum
Esculin
7-Hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl) tetrahydro-2H-pyran-2-yl]oxy}-2H-chromen- 2-unus
6-(β-D-Glucopyranosyloxy) -7-hydroxy-2H-1-benzopyran-2-unum
Esculetin 6-bD-glucoside
2H-1-Benzopyran-2-se, 6-(β-D-glucopyranosyloxy)-7-hydroxy-
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside hydratum (1:1)
Aesculin
MCD00006879
Esculetin-6-O-glucoside
2H-1-Benzopyran-2-unum, 6-(β-D-glucopyranosyloxy) -7-hydroxy-, hydratum (1: 1).
Escosyl
