Paeoniflorin CAS Nama 23180-57-6
Nga korero tino nui
E mohiotia ana ano ko te paeoniflorin, he pinane monoterpene kawa glycoside kua wehea mai i te peony whero me te peony ma.He paura amorphous hygroscopic.Kei roto i nga pakiaka o Paeonia, peony, peony papura me etahi atu tipu o Ranunculaceae.He iti rawa te paitini o tenei karaihe.
[ingoa matū]5beta-[(Benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1alpha(2H)-yl-beta-D-glucopyranoside
[tauira rāpoi]C23H28O11
【CASKao】23180-57-6
Maamaa: i runga ake i te 98%, tikanga rapu: HPLC.
[puna]nga pakiaka o Paeonia albiflora pall, P. suffrsticosa Andr, P. delarayi Franch, he tipu o Ranunculaceae, ko te mea nui o te radix paeoniae Rubr te mea teitei.
[Whakaahuatanga]10%，20%，30%，50%，90% ， 98%
[AmahiIwhakaurunga ] Ko nga glucosides katoa o Paeonia (TGP) te ingoa whanui o te paeoniflorin, te hydroxy paeoniflorin, te paeoniflorin, te albiflorin me te benzoyl paeoniflorin, e kiia nei ko TGP mo te poto.
Ngā āhuatanga ā-tinana me te matū
He hygroscopic amorphous Tan paura (90% he paura ma)[ α] 16D-12.8。 (C = 4.6, methanol), te tetraacetate he karaihe acicular taekore, ira whakarewa: 196 ℃.Ko te Paeoniflorin he pumau i roto i te taiao waikawa (pH 2 ~ 6) me te pahekeheke i te taiao kawakore.
Te Whakatau Ihirangi
Ko te tikanga, ka taea hoki te whakamahi tikanga 1 me te tikanga 2 mo te rapu.Ko te tikanga 1 he pai ake te whakamahi mo te whakaputa ihirangi tiketike, ka awhina i nga kaimahi ki te whakahaere kia pai ake te whakatau i te ma o nga hua.Ko te matū tohutoro he ngawari ki te pirau i muri i te whakakorenga.
1.I whakatauhia e te chromatography wai mahi teitei (Appendix VI d).I whakamatauria nga ahuatanga chromatographic me te pai o te punaha me te Octadecyl silane herea silica gel hei whakakii;Ko te Acetonitrile-0.1% te wairewa waikawa phosphoric (14:86) i whakamahia hei waahanga pūkoro;Ko te roangaru kitea he 230nm.Ko te maha o nga pereti ariā kua tatauhia kia rite ki te tihi paeoniflorin kaua e iti iho i te 2000. Te takahanga o te otinga tohutoro: tika te pauna i te nui o te otinga tohutoro paeoniflorin me te taapiri i te methanol hei whakarite i te 60% paeoniflorin mo te otinga 1ml μG.
2.Hei whakapai ake i te tikanga whakatau paeoniflorin i Radix Paeoniae Alba.Nga tikanga: ko nga tikanga i roto i te Hainamana Pharmacopoeia me nga tikanga pai ake i whakaritea.Ko te wahanga pūkoro he wai methanol (30:70) me te roangaru kitea he 230nm.hua;He pai te hononga rarangi o tenei tikanga (r = 0.9995).Ko te whakaoranga toharite ko 101.518% me te RSD ko 1.682%.Whakamutunga: ko te tikanga whakapai ake he maamaa me te tika, ka taea te whakaiti i te paitini o nga whakarewa pararopi ki te tangata me te poke o te taiao, me te whakarato i te kaupapa tohutoro mo te whakatau i te paeoniflorin i roto i te mahi.
Tikanga Whakatau
Te whakatau i te paeoniflorin na HPLC
Te whānuitanga o te tono:ka whakamahia e tenei tikanga te HPLC hei whakatau i te ihirangi o te paeoniflorin i nga pire Guizhi Fuling.
He pai te tikanga mo te pire Guizhi Fuling.
Tikanga tikanga:hoatu te tauira whakamātautau ki roto i te ipu koeko, tāpirihia he nui e tika ana o te waihā waimeha mo te tangohanga ultrasonic, whakamataohia, ruru pai, tātarihia, ka uru te filtrate ki te chromatograph wai tino mahi mo te wehenga chromatographic, whakamahia te kaitirotiro whakaurunga ultraviolet ki te kitea te uara absorption o paeoniflorin i te roangaru o te 230nm, me te tatau i ona ihirangi.
