Paeoniflorin CAS No. 23180-57-6
Ruzivo Rwakakosha
Iyo inozivikanwawo se paeoniflorin, ipinane monoterpene inovava glycoside yakaparadzaniswa kubva kune tsvuku peony uye chena peony.Ndiyo hygroscopic amorphous powder.Inowanikwa mumidzi yePaeonia, peony, peony peony nemimwe miti yeRanunculaceae.Hupfu hwekristaro iyi hwakaderera.
[zita remakemikari]5beta- [(Benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1alpha(2H)-yl-beta-D-glucopyranoside
[molecular formula]C23H28O11
【CASAihwa】23180-57-6
Kuchena: pamusoro pe98%, nzira yekuona: HPLC.
[mabviro]the roots of Paeonia albiflora pall, P. suffrsticosa Andr, P. delarayi Franch, chirimwa cheRanunculaceae, zviri mu radix paeoniae Rubr ndizvo zvakakwirira.
[Mashoko]10%, 20%, 30%, 50%, 90%, 98%
[ActiveIingredient ] Total glucosides of Paeonia (TGP) izita rinowanzozivikanwa repaeoniflorin, hydroxy paeoniflorin, paeoniflorin, albiflorin uye benzoyl paeoniflorin, inodaidzwa kuti TGP muchidimbu.
Zvenyama uye zvemakemikari zvinhu
Iine hygroscopic amorphous Tan powder (90% inobva paupfu chena) [α] 16D-12.8. (C = 4.6, methanol), tetraacetate haina ruvara acicular crystal, inonyunguduka: 196 ℃.Paeoniflorin yakagadzikana munzvimbo ine acidic (pH 2 ~ 6) uye isina kugadzikana munzvimbo yealkaline.
Content Determination
Kazhinji, nzira 1 uye nzira 2 inogona kushandiswawo kuona.Nzira yekutanga inoshandiswa zvakanyanya pakugadzirwa kwepamusoro, iyo inogona kubatsira kugadzirisa vashandi zviri nani kutonga kuchena kwezvigadzirwa.Chinhu chinorehwa chiri nyore kuora mushure mekuparadzwa.
1.Yakagadziriswa nepamusoro pekuita liquid chromatography (Appendix VI d).Mamiriro echromatographic uye kukodzera kwehurongwa kwakaedzwa neOctadecyl silane yakasungirirwa silica gel sekuzadza;Acetonitrile-0.1% phosphoric acid solution (14:86) yakashandiswa sechikamu chekufambisa;Iyo yekuona wavelength ndeye 230nm.Nhamba yezvinyorwa zvezvinyorwa zvakaverengerwa maererano nepeoniflorin peak haifaniri kuva pasi pe 2000. Kugadzirira kwekugadzirisa mhinduro: kunyatsoyera huwandu hwakakodzera hwepaeoniflorin reference solution uye kuwedzera methanol kugadzirira 60% paeoniflorin pa 1ml μ G solution.
2.Kuvandudza nzira yekutsunga ye paeoniflorin muRadix Paeoniae Alba.Nzira: nzira dzeChinese Pharmacopoeia uye nzira dzakavandudzwa dzakaenzaniswa.Nharembozha yaive mvura yemethanol (30:70) uye iyo yekuona wavelength yaive 230nm.result;Ukama hwemutsara weiyi nzira yakanaka (r = 0.9995).Avhareji yekupora ndeye 101.518% uye RSD ndeye 1.682%.Mhedziso: nzira yakagadziridzwa iri nyore uye yakarurama, iyo inogona kuderedza huturu hwezvinonyungudutsa zvehupenyu kuvanhu uye kusvibiswa kwezvakatipoteredza, uye kupa chirevo chekutsvaga kwekugadzirisa paeoniflorin mukuita.
Kutsunga Nzira
Kutsunga kwepaeoniflorin neHPLC
Chikamu chekushandisa:nzira iyi inoshandisa HPLC kuona zvirimo paeoniflorin muGuizhi Fuling mapiritsi.
Iyo nzira yakakodzera Guizhi Fuling piritsi.
Nzira musimboti:isa sampu yekuyedza muconical flask, wedzera huwandu hwakakodzera hwe dilute ethanol yekutorwa kwe ultrasonic, itonhodze, izunze zvakanaka, isasefa, iyo filtrate inopinda mune yakakwira performance liquid chromatograph yekuparadzanisa chromatographic, shandisa ultraviolet absorption detector kuona Kunyura kukosha kwepaeoniflorin pakureba kwe230nm, uye verenga zvirimo.
